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. 2021 Sep 30;224(12 Suppl 2):S379-S386.
doi: 10.1093/infdis/jiaa588.

Smallpox

Joel G Breman  1
Affiliations

Smallpox

Joel G Breman. J Infect Dis. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Bifurcated needle for intradermal injection of vaccinia virus, invented by Benjamin Rubin (left) of Wyeth Laboratories. (Source: Fenner et al [2], WHO.)
Figure 2.
Figure 2.
Jet injector for intradermal injection of vaccinia virus. Top left, Intradermal nozzle squirts at an angle for smallpox vaccination. Top right, Jet Injector in its case. The instruction book for West Africa was in English and French. Bottom right, Aaron Ismach, who is credited with the design of this injector. (Source: WHO, CDC)
Figure 3.
Figure 3.
Skin reaction after primary vaccination and late revaccination (several years later), performed using a multiple puncture method or a jet injector. (Source: CDC.)
Figure 4.
Figure 4.
Accidental autoinoculation of cheek with vaccinia virus, approximately 5 days old. Primary take with “Jennerian vesicle” on arm, 10–12 days old. (Photograph courtesy of John M. Leedom, MD, CDC collection.)
Figure 5.
Figure 5.
Smallpox on day 8 of eruption (World Health Organization photograph).
Figure 6.
Figure 6.
Last case patient with Variola major smallpox (Bangladesh, 1975). (Source: World Health Organization.)
Figure 7.
Figure 7.
Last case patient with naturally transmitted smallpox (October 1977). (Source: World Health Organization.)
See this image and copyright information in PMC

References

    1. Fenner F, Henderson DA, Arita I, Ježek Z, Ladnyi ID.. Smallpox and its eradication. Geneva, Switzerland: World Health Organization, 1988.
    1. Baxby D. Two hundred years of vaccination. Curr Biol 1996; 6:769–72. - PubMed
    1. Baxby D.Jenner’s smallpox vaccine: the riddle of vaccinia virus and its origin. Vol 14. London, United Kingdom: Heinemann Educational Books, 1981.
    1. Henderson DA.Smallpox—the death of a disease: the inside story of eradicating a worldwide killer. Amherst, New York: Prometheus Books, 2009.
    1. Collier LH. Appropriate technology in the development of freeze-dried smallpox vaccine. WHO Chron 1980; 34:178–9. - PubMed

Publication types

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