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. 2021:2357:197-208.
doi: 10.1007/978-1-0716-1621-5_13.

Detecting Persister Awakening Determinants

Dorien Wilmaerts  1   2 , Jan Michiels  3   4 , Natalie Verstraeten  1   2
Affiliations

Detecting Persister Awakening Determinants

Dorien Wilmaerts et al. Methods Mol Biol. 2021.

Abstract

For long, persistence research has focused primarily on disentangling mechanisms of persister state entry. Due to the rapid advances in the field of single-cell techniques and newly obtained insights in the persister phenotype, studying persister awakening has been unlocked and it has gained much interest in the scientific community. However, a framework on how this research should be conducted is currently lacking. Therefore, we here present a method to detect and validate genes important for persister awakening.

Keywords: Cell sorting; Persister; Persister awakening; Single-cell.

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References

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