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. 2021 Oct 7;27(56):13897-13898.
doi: 10.1002/chem.202103349. Epub 2021 Sep 30.

Amine-Directed Palladium-Catalyzed C-H Halogenation of Phenylalanine Derivatives

Alexia Ville  1 , Julien Annibaletto  1 , Sébastien Coufourier  1   2 , Christophe Hoarau  1 , Rodolphe Tamion  2 , Guillaume Journot  2 , Cédric Schneider  1 , Jean-François Brière  1
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Amine-Directed Palladium-Catalyzed C-H Halogenation of Phenylalanine Derivatives

Alexia Ville et al. Chemistry. .

Abstract

Invited for the cover of this issue are Jean-François Brière, Cédric Schneider, Guillaume Journot and co-workers from the COBRA laboratory and Oril Industrie (Normandy, France). The image shows the progression from questioning how to easily and regioselectively introduce halogen atoms to amino acids to the discovery of a catalytic functional-group-directed C-H halogenation of phenylalanine derivatives. Read the full text of the article at 10.1002/chem.202102411.

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