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. 2019 Dec;1(4):56-61.

One Hundred Years of Influenza Since the 1918 Pandemic - Is China Prepared Today?

Ran Zhang  1 , Xiaoping Dong  2 , Dayan Wang  3 , Luzhao Feng  2 , Lei Zhou  2 , Ruiqi Ren  2 , Carolyn Greene  1 , Ying Song  1 , Alexander J Millman  1 , Eduardo Azziz-Baumgartner  1 , Zijian Feng  2
Affiliations

One Hundred Years of Influenza Since the 1918 Pandemic - Is China Prepared Today?

Ran Zhang et al. China CDC Wkly. 2019 Dec.

Abstract

Almost 100 years after the 1918 influenza pandemic, China experienced its largest, most widespread epidemic of human infections with avian influenza A (H7N9), the influenza virus with the greatest pandemic potential of all influenza viruses assessed to date by the United States Centers for Disease Control and Prevention's Influenza Risk Assessment Tool. This historical review describes how China was affected by the 1918, 1958, 1968, and 2009 influenza pandemics, records milestones in China's capacity to detect and respond to influenza threats, and identifies remaining challenges for pandemic preparedness. This review suggests that past influenza pandemics have improved China's national capabilities such that China has become a global leader in influenza detection and response. Further enhancing China's pandemic preparedness to address remaining challenges requires government commitment and increased investment in China's public health and healthcare systems.

Keywords: Avian Influenza A(H7N9); China; Influenza Pandemic; Pandemic Preparedness.

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Figures

Figure 1
Figure 1
Influenza pandemics, scientific discoveries and China’s influenza-related capacity milestones, 1918–2018.
See this image and copyright information in PMC

References

    1. Murray CJ, Lopez AD, Chin B, Feehan D, Hill KH Estimation of potential global pandemic influenza mortality on the basis of vital registry data from the 1918-20 pandemic: a quantitative analysis. Lancet. 2006;368(9554):2211–8. doi: 10.1016/S0140-6736(06)69895-4. - DOI - PubMed
    1. Kile JC, Ren R, Liu L, Greene CM, Roguski C, Iuliano AD, et al Update: Increase in Human Infections with Novel Asian Lineage Avian Influenza A(H7N9) Viruses During the Fifth Epidemic - China, October 1, 2016-August 7, 2017. MMWR Morb Mortal Wkly Rep. 2017;66(35):928–32. doi: 10.15585/mmwr.mm6635a2. - DOI - PMC - PubMed
    1. Cheng KF, Leung PC What happened in China during the 1918 influenza pandemic? Int J Infect Dis. 2007;11(4):360–4. doi: 10.1016/j.ijid.2006.07.009. - DOI - PubMed
    1. Johnson NP, Mueller J Updating the accounts: global mortality of the 1918-1920 “Spanish” influenza pandemic. Bull Hist Med. 2002;76(1):105–15. doi: 10.1353/bhm.2002.0022. - DOI - PubMed
    1. Kilbourne ED Influenza pandemics of the 20th century. Emerg Infect Dis. 2006;12(1):9–14. doi: 10.3201/eid1201.051254. - DOI - PMC - PubMed

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