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Case Reports
. 2022 Jan 1;41(1):e16-e18.
doi: 10.1097/INF.0000000000003358.

Acute Cerebellitis in MIS-C: A Case Report

Nihal Akçay  1 , Mustafa Oğur  1 , Mehmet Emin Menentoğlu  1 , Ayşe İrem Sofuoğlu  1 , Kübra Boydağ Güvenç  1 , Figen Bakirtaş Palabiyik  2 , Esra Şevketoğlu  1
Affiliations
Case Reports

Acute Cerebellitis in MIS-C: A Case Report

Nihal Akçay et al. Pediatr Infect Dis J. .

Abstract

Background: Coronavirus disease-2019 (COVID-19) is characterized predominantly by respiratory symptoms and has affected a small subset of children. Multisystem inflammatory syndrome in children (MIS-C) has been reported in children following COVID-19. There is increasing report that COVID-19 may also lead to neurologic manifestations. Cerebellar lesions may be observed in viral infections.

Case report: We report a child with MIS-C related to severe acute respiratory syndrome coronavirus 2, who developed cerebellar lesion during the disease course. Encephalopathy was the first central nervous system symptom. His consciousness improved but he developed clinical signs of cerebellar dysfunction including ataxia, dysarthria and nystagmus. Brain magnetic resonance imaging (MRI) revealed symmetrical pathological signal changes in both cerebellar hemispheres.

Conclusion: We demonstrated the first child with MIS-C to develop cerebellar lesion on brain MRI, suggestive of cerebellitis.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

Figures

FIGURE 1.
FIGURE 1.
Brain MRI of patient. T2A (A), FLAIR (B) and DWI (C) sequences in the cranial MRI examination of the case taken during the first admission no pathology was observed. However, in the control cranial MRI taken 6 days later, symmetrical pathological signal changes were observed in T2W (D) and FLAIR (E) sequences in both cerebral hemispheres, and these lesions showed restriction in DWI (F). MRI indicates magnetic resonance imaging.
See this image and copyright information in PMC

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Publication types

Supplementary concepts