Welcoming c-MAF to the macrophage transcription factor VAM-ily
- PMID: 34597120
- DOI: 10.1126/sciimmunol.abl5793
Welcoming c-MAF to the macrophage transcription factor VAM-ily
Abstract
The transcription factor c-MAF regulates perivascular macrophage phenotypes across tissues, including white adipose tissue, where its loss from murine vasculature–associated macrophages leads to increased vascularization and protection from metabolic syndrome (see the related Research Article by Moura Silva et al.).
Comment on
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c-MAF-dependent perivascular macrophages regulate diet-induced metabolic syndrome.Sci Immunol. 2021 Oct;6(64):eabg7506. doi: 10.1126/sciimmunol.abg7506. Epub 2021 Oct 1. Sci Immunol. 2021. PMID: 34597123
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