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. 2022 May;37(5):1087-1096.
doi: 10.1007/s00467-021-05224-3. Epub 2021 Oct 1.

Validity and reliability of the Dutch version of the PedsQL™ 3.0 End Stage Renal Disease Module in children with chronic kidney disease in Belgium

Elke De Bruyne  1 , Sunny Eloot  2 , Johan Vande Walle  3 , Ann Raes  3 , Wim Van Biesen  2 , Liesbet Goubert  4 , Tine Vervoort  4 , Evelien Snauwaert #  2 , Eline Van Hoecke #  5
Affiliations

Validity and reliability of the Dutch version of the PedsQL™ 3.0 End Stage Renal Disease Module in children with chronic kidney disease in Belgium

Elke De Bruyne et al. Pediatr Nephrol. 2022 May.

Abstract

Background: Children with chronic kidney disease (CKD) have a low quality of life (QoL). The PedsQL™ 4.0 Generic Core Scales are widely used to assess general QoL in children. The aim of this cross-sectional study was to translate the original version of the CKD-specific PedsQL™ 3.0 End Stage Renal Disease Module into a Dutch version and to evaluate its validity and reliability.

Methods: The forward-backward translation method based on the guidelines from the original developer was used to produce the Dutch version of the PedsQL™ 3.0 ESRD Module. Fifty-eight CKD patients (aged 8-18 years) and their parents (n = 31) filled in both generic and disease-specific modules. The non-clinical control group consisted of the same number of healthy children (matched for gender and age) and their parents.

Results: Cronbach's alpha coefficients (α's) for the PedsQL™ 3.0 ESRD Module demonstrated excellent reliability for the Total Scale scores. For all 7 subscales, α's were greater than 0.60, except for Perceived Physical Appearance. Overall, intercorrelations with the PedsQL™ 4.0 Generic Core Scales were in the medium to large range, supporting construct validity. Parent proxy reports showed lower generic QoL for all domains in CKD patients compared to healthy children. Child self-reports only demonstrated lower QoL on the domain School Functioning in children with CKD compared to healthy children.

Conclusions: This study shows good validity and reliability for the Dutch version of the PedsQL™ 3.0 ESRD Module. However, testing with a larger study group is recommended in order to make final conclusions about the psychometric qualities of this measure. A higher resolution version of the Graphical abstract is available as Supplementary information.

Keywords: Children; Chronic kidney disease; PedsQL™; Quality of life; Reliability; Validity.

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References

    1. McDonald SP, Craig JC (2004) Long-term survival of children with end-stage renal disease. N Engl J Med 350:2654–2662. https://doi.org/10.1056/NEJMoa031643 - DOI - PubMed
    1. Goldstein SL, Graham N, Warady BA, Seikaly M, McDonald R, Burwinkle TM, Limbers CA, Vami JW (2008) Measuring health-related quality of life in children with ESRD: performance of the generic and ESRD-specific instrument of the pediatric quality of life inventory (PedsQL). Am J Kidney Dis 51:285–297. https://doi.org/10.1053/j.ajkd.2007.09.021 - DOI - PubMed
    1. Marciano RC, Soares CMB, Diniz JSS, Lima EM, Silva JMP, Canhestro MR, Gazzinelli A, Melo CCD, Dias CS, Silva A, Correa H, Oliveira EA (2011) Behavioral disorders and low quality of life in children and adolescents with chronic kidney disease. Pediatr Nephrol 26:281–290. https://doi.org/10.1007/s00467-010-1683-y - DOI - PubMed
    1. Gerson A, Hwang W, Fiorenza J, Barth K, Kaskel F, Weiss L, Zelikovsky N, Fivush B, Furth S (2004) Anemia and health-related quality of life in adolescents with chronic kidney disease. Am J Kidney Dis 44:1017–1023. https://doi.org/10.1053/j.ajkd.2004.08.024 - DOI - PubMed
    1. Fadrowski J, Cole SR, Hwang WK, Fiorenza J, Weiss RA, Gerson A, Furth SL (2006) Changes in physical and psychosocial functioning among adolescents with chronic kidney disease. Pediatr Nephrol 21:394–399. https://doi.org/10.1007/s00467-005-2122-3 - DOI - PubMed

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