Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Sep 30;94(3):497-507.
eCollection 2021 Sep.

An Overview of Health Disparities in Asthma

Affiliations
Review

An Overview of Health Disparities in Asthma

Mario F Perez et al. Yale J Biol Med. .

Abstract

Asthma is a heterogeneous disease characterized by inflammation in the respiratory airways which manifests clinically with wheezing, cough, and episodic periods of chest tightness; if left untreated it can lead to permanent obstruction or death. In the US, asthma affects all ages and genders, and individuals from racial and ethnic minority groups are disproportionately burdened by this disease. The financial cost of asthma exceeds $81 billion every year and despite all the resources invested, asthma is responsible for over 3,500 deaths annually in the nation. In this overview, we highlight important factors associated with health disparities in asthma. While they are complex and overlap, we group these factors in five domains: biological, behavioral, socio-cultural, built environment, and health systems. We review the biological domain in detail, which traditionally has been best studied. We also acknowledge that implicit and explicit racism is an important contributor to asthma disparities and responsible for many of the socio-environmental factors that worsen outcomes in this disease.

Keywords: Asthma; Health Disparities.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Trend in asthma prevalence in the US among Whites, African Americans and Hispanics from 2007 to 2017. Source: Center for Disease Control and Prevention. https://www.cdc.gov/asthma/national-surveillance-data/default.htm
Figure 2
Figure 2
Factors that contribute to persistent health disparities in asthma.

Similar articles

Cited by

References

    1. CDC. Most Recent National Asthma Data: National Center for Environmental Health; 2020. [cited 2021 February 28]. Available from: https://www.cdc.gov/asthma/most_recent_national_asthma_data.htm
    1. Global Initiative for Asthma. 2020. [cited 2021 February 12]. Available from: https://ginasthma.org/
    1. Nurmagambetov T, Kuwahara R, Garbe P. The Economic Burden of Asthma in the United States, 2008-2013. Ann Am Thorac Soc. 2018March;15(3):348–56. 10.1513/AnnalsATS.201703-259OC - DOI - PubMed
    1. Inselman JW, Jeffery MM, Maddux JT, Shah ND, Rank MA. Trends and Disparities in Asthma Biologic Use in the United States. J Allergy Clin Immunol Pract. 2020;8(2):549-54.e1. Epub 08/28. doi: 10.1016/j.jaip.2019.08.024. - DOI - PMC - PubMed
    1. Pennington E, Yaqoob ZJ, Al-Kindi SG, Zein J. Trends in Asthma Mortality in the United States: 1999 to 2015. Am J Respir Crit Care Med. 2019June;199(12):1575–7. 10.1164/rccm.201810-1844LE - DOI - PMC - PubMed

Publication types