No abstract available
Keywords:
VSD gate coupling; cryo-EM; patch - clamp technique; toxins; voltage-gated ion channel.
PubMed Disclaimer
Conflict of interest statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Comment on
-
Editorial on the Research Topic Molecular Mechanisms of Voltage-Gating in Ion Channels
References
-
-
Choveau F. S., Rodriguez N., Abderemane Ali F., Labro A. J., Rose T., Dahimène S., et al. (2011). KCNQ1 Channels Voltage Dependence through a Voltage-dependent Binding of the S4-S5 Linker to the Pore Domain. J. Biol. Chem. 286, 707–716. 10.1074/jbc.M110.146324
-
DOI
-
PMC
-
PubMed
-
-
Loussouarn G., Tarek M. (2012). Mechanisms of Ion Channels Voltage-Dependency: All about Molecular Sensors, Gates, Levers, Locks, and Grease. Front. Pharmacol. 3, 174. 10.3389/fphar.2012.00174
-
DOI
-
PMC
-
PubMed
-
-
Malak O. A., Es-Salah-Lamoureux Z., Loussouarn G. (2017). hERG S4-S5 Linker Acts as a Voltage-dependent Ligand that Binds to the Activation Gate and Locks it in a Closed State. Sci. Rep. 7, 113. 10.1038/s41598-017-00155-2
-
DOI
-
PMC
-
PubMed
-
-
Malak O. A., Gluhov G. S., Grizel A. V., Kudryashova K. S., Sokolova O. S., Loussouarn G. (2019). Voltage-dependent Activation in EAG Channels Follows a Ligand-Receptor rather Than a Mechanical-Lever Mechanism. J. Biol. Chem. 294, 6506–6521. 10.1074/jbc.RA119.007626
-
DOI
-
PMC
-
PubMed