Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Sep 16:11:758143.
doi: 10.3389/fonc.2021.758143. eCollection 2021.

Advanced Nano-Carriers for Anti-Tumor Drug Loading

Affiliations
Review

Advanced Nano-Carriers for Anti-Tumor Drug Loading

Jia Xiang et al. Front Oncol. .

Abstract

Chemotherapy is one of the important means of tumor therapy. However, most of the anti-tumor drugs that currently used in clinic are hydrophobic non-specific drugs, which seriously affect the efficacy of drugs. With the development of nanotechnology, drug efficacy can be improved by selecting appropriate biodegradable nanocarriers for achieving the controlled release, targeting and higher bioavailability of drugs. This paper reviewed the research progress of anti-tumor drug nanoparticle carriers, which mainly summarized the materials used for anti-tumor drug nanoparticle carriers and their effects in anti-tumor drugs, as well as the targeted drug delivery methods of anti-tumor drugs based on nanocarriers.

Keywords: antitumor drug; cancer; chemotherapy; nano drug carrier; targeted transportation.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor declared a shared affiliation, though no other collaboration with the authors at the time of the review.

Figures

Figure 1
Figure 1
Development of nano-carriers for anti-tumor drug.

Similar articles

Cited by

References

    1. Nygren P. What Is Cancer Chemotherapy? Acta Oncol (2001) 40(2–3):166–74. doi: 10.1080/02841860151116204 - DOI - PubMed
    1. Chen H, Zheng Y, Tian G, Tian Y, Zeng X, Liu G, et al. . Oral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy. Nanoscale Res Lett (2011) 6(1):4. doi: 10.1007/s11671-010-9741-8 - DOI - PMC - PubMed
    1. Jain KK. An Overview of Drug Delivery Systems. Methods Mol Biol (2020) 1–54. doi: 10.1007/978-1-4939-9798-5_1 - DOI - PubMed
    1. Van Vlerken LE, Amiji MM. Multi-Functional Polymeric Nanoparticles for Tumour-Targeted Drug Delivery. Expert Opin Drug Deliv (2006) 3(2):205–16. doi: 10.1517/17425247.3.2.205 - DOI - PubMed
    1. Kreuter J. Nanoparticles—A Historical Perspective. Int J Pharmaceut (2007) 331(1):1–10. doi: 10.doi:10.1016/j.ijpharm.2006.10.021 - PubMed

LinkOut - more resources