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Review
. 2021 Sep 9:2:329-340.
doi: 10.1016/j.crtox.2021.09.001. eCollection 2021.

Venom peptides - A comprehensive translational perspective in pain management

Vidya V  1 , Raghu Ram Achar  2 , Himathi M U  2 , Akshita N  2 , Yogish Somayaji T  3 , Vivek Hamse Kameshwar  4   5 , K Byrappa  5   6 , Dinesha Ramadas  7
Affiliations
Review

Venom peptides - A comprehensive translational perspective in pain management

Vidya V et al. Curr Res Toxicol. .

Abstract

Venom peptides have been evolving complex therapeutic interventions that potently and selectively modulate a range of targets such as ion channels, receptors, and signaling pathways of physiological processes making it potential therapeutic. Several venom peptides were deduced in vivo for clinical development targeting pain management, diabetes, cardiovascular diseases, antimicrobial activity. Several contributions have been detailed for a clear perspective for a better understanding of venomous animals, their venom, and their pharmacological effects. Here we unravel and summarize the recent advances in wide venom peptides across varieties of species for their therapeutics prospects.

Keywords: Inflammation; Nociception; Pain; Peptides; Snake venom; Toxicity; Toxins.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

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Graphical abstract
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