Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep 27;2(5):e12562.
doi: 10.1002/emp2.12562. eCollection 2021 Oct.

Acute SARS-CoV-2 infection and reversible splenial hyperintensity: A stroke mimic

Thomas Mathew  1 , Saji K John  1 , Sharath Kumar G G  1
Affiliations

Acute SARS-CoV-2 infection and reversible splenial hyperintensity: A stroke mimic

Thomas Mathew et al. J Am Coll Emerg Physicians Open. .
No abstract available

Keywords: COVID‐19 infection; dot sign; transient splenial sign.

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1
Magnetic resonance imaging of the brain done on April 30, 2021: (A) Diffusion weighted image showing restriction in the splenium of corpus callosum suggestive of Transient splenial sign or Dot sign (white arrow) (B) MRI of the brain FLAIR image is normal
FIGURE 2
FIGURE 2
Repeat Magnetic resonance imaging of the brain done on June 17, 2021 showing complete resolution of the lesion
See this image and copyright information in PMC

References

    1. Malhotra HS, Garg RK, Vidhate MR, Sharma PK. Boomerang sign: clinical significance of transient lesion in splenium of corpus callosum. Ann Indian Acad Neurol. 2012;15(2):151‐157. - PMC - PubMed
    1. Starkey J, Kobayashi N, Numaguchi Y, Moritani T. Cytotoxic lesions of the corpus callosum that show restricted diffusion: mechanisms, causes, and manifestations. Radiographics. 2017;37(2):562‐576. - PubMed
    1. Hayashi M, Sahashi Y, Baba Y, Okura H, Shimohata T. COVID‐19‐associated mild encephalitis/encephalopathy with a reversible splenial lesion. J Neurol Sci. 2020;415:116941. - PMC - PubMed
    1. Forestier G, de Beaurepaire I, Bornet G, et al. Cytotoxic lesion of the corpus callosum as presenting neuroradiological manifestation of COVID‐2019 infection. J Neurol. 2021;268:1595‐1597. - PMC - PubMed