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Randomized Controlled Trial
. 2021 Dec;44(6):945-956.
doi: 10.1002/nur.22187. Epub 2021 Oct 3.

Effectiveness of progressive muscle relaxation and laughter therapy on mental health and treatment outcomes in women undergoing in vitro fertilization: A randomized controlled trial

Sibel Kiyak  1 , Deniz Kocoglu-Tanyer  2
Affiliations
Randomized Controlled Trial

Effectiveness of progressive muscle relaxation and laughter therapy on mental health and treatment outcomes in women undergoing in vitro fertilization: A randomized controlled trial

Sibel Kiyak et al. Res Nurs Health. 2021 Dec.

Abstract

A majority of infertile women experience emotional problems, such as anxiety and depression. Nurses need nonpharmacological methods rather than drugs to address women's emotional distress during the in vitro fertilization (IVF) process. The purpose of this study was to examine the effect of progressive muscle relaxation exercises and laughter therapy on the mental health and treatment outcomes of women receiving IVF treatment. This parallel-group, randomized controlled trial was conducted in a private IVF center. Participants were randomly assigned to the intervention group (IG; n = 71) and control group (CG; n = 70). The IG received progressive muscle relaxation and laughter therapy for 40 min in each session for 3-4 sessions, whereas the CG received routine care. Data were obtained from the patient information form, State-Trait Anxiety Inventory, Beck Depression Inventory, and medical records. The questionnaire was completed at recruitment (T1) and oocyte pick-up day (T2). In the evaluation performed on the day of the oocyte pick-up, depression and trait anxiety scores of the IG were found to be lower than those in the CG, and the effect size was small. Group × time interaction was significant for depression (large effect size) and trait anxiety (small effect size). The estradiol levels, the number of oocytes, transfer status, and pregnancy rates (according to a blood test) were similar between groups. Women receiving IVF treatment who received progressive muscle relaxation and laughter therapy demonstrated psychological changes; however, the treatment did not affect medical outcomes.

Keywords: anxiety; depression; infertility; laughter therapy; progressive muscle relaxation.

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References

REFERENCES

    1. Aimagambetova, G., Issanov, A., Terzic, S., Bapayeva, G., Ukybassova, T., Baikoshkarova, S., Aldiyarova, A., Shauyen, F., & Terzic, M. (2020). The effect of psychological distress on IVF outcomes: Reality or speculations? PLoS One, 15(12), e0242024. https://doi.org/10.1371/journal.pone.0242024
    1. Ali, H., & Elagamy, M. A. E. E. (2021). Effectiveness of progressive muscle relaxation on minimizing stress among women with infertility. Egyptian Journal of Health Care, 12(2), 255-264.
    1. An, Y., Sun, Z., Li, L., Zhang, Y., & Ji, H. (2013). Relationship between psychological stress and reproductive outcome in women undergoing in vitro fertilization treatment: Psychological and neurohormonal assessment. Journal of Assisted Reproduction and Genetics, 30(1), 35-41. https://doi.org/10.1007/s10815-012-9904-x
    1. Anu, C. V. (2011). Effectiveness of progressive muscle relaxation technique on stress, anxiety and depression in infertile women at a selected hospital, Erode [Master's thesis, Sri Gokulam College of Nursing]. http://repository-tnmgrmu.ac.in/4533/
    1. Armat, M. R., Emami Zeydi, A., Mokarami, H., Nakhlband, A., & Hojjat, S. K. (2020). The impact of laughter yoga on depression and anxiety among retired women: A randomized controlled clinical trial. Journal of Women & Aging. Advance online publication. 1-12. https://doi.org/10.1080/08952841.2020.1774225

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