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. 2022 Feb 15:299:367-376.
doi: 10.1016/j.jad.2021.09.090. Epub 2021 Oct 2.

Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A)

Marco Solmi  1 Andrés Estradé  2 Trevor Thompson  3 Agorastos Agorastos  4 Joaquim Radua  5 Samuele Cortese  6 Elena Dragioti  7 Friedrich Leisch  8 Davy Vancampfort  9 Lau Caspar Thygesen  10 Harald Aschauer  11 Monika Schloegelhofer  12 Elena Akimova  13 Andres Schneeberger  14 Christian G Huber  15 Gregor Hasler  16 Philippe Conus  17 Kim Q Do Cuénod  18 Roland von Känel  19 Gonzalo Arrondo  20 Paolo Fusar-Poli  21 Philip Gorwood  22 Pierre-Michel Llorca  23 Marie-Odile Krebs  24 Elisabetta Scanferla  25 Taishiro Kishimoto  26 Golam Rabbani  27 Karolina Skonieczna-Żydecka  28 Paolo Brambilla  29 Angela Favaro  30 Akihiro Takamiya  31 Leonardo Zoccante  32 Marco Colizzi  33 Julie Bourgin  34 Karol Kamiński  35 Maryam Moghadasin  36 Soraya Seedat  37 Evan Matthews  38 John Wells  39 Emilia Vassilopoulou  40 Ary Gadelha  41 Kuan-Pin Su  42 Jun Soo Kwon  43 Minah Kim  44 Tae Young Lee  45 Oleg Papsuev  46 Denisa Manková  47 Andrea Boscutti  48 Cristiano Gerunda  49 Diego Saccon  50 Elena Righi  51 Francesco Monaco  52 Giovanni Croatto  53 Guido Cereda  54 Jacopo Demurtas  55 Natascia Brondino  56 Nicola Veronese  57 Paolo Enrico  58 Pierluigi Politi  59 Valentina Ciappolino  60 Andrea Pfennig  61 Andreas Bechdolf  62 Andreas Meyer-Lindenberg  63 Kai G Kahl  64 Katharina Domschke  65 Michael Bauer  66 Nikolaos Koutsouleris  67 Sibylle Winter  68 Stefan Borgwardt  69 Istvan Bitter  70 Judit Balazs  71 Pal Czobor  72 Zsolt Unoka  73 Dimitris Mavridis  74 Konstantinos Tsamakis  75 Vasilios P Bozikas  76 Chavit Tunvirachaisakul  77 Michael Maes  78 Teerayuth Rungnirundorn  79 Thitiporn Supasitthumrong  80 Ariful Haque  81 Andre R Brunoni  82 Carlos Gustavo Costardi  83 Felipe Barreto Schuch  84 Guilherme Polanczyk  85 Jhoanne Merlyn Luiz  86 Lais Fonseca  87 Luana V Aparicio  88 Samira S Valvassori  89 Merete Nordentoft  90 Per Vendsborg  91 Sofie Have Hoffmann  92 Jihed Sehli  93 Norman Sartorius  94 Sabina Heuss  95 Daniel Guinart  96 Jane Hamilton  97 John Kane  98 Jose Rubio  99 Michael Sand  100 Ai Koyanagi  101 Aleix Solanes  102 Alvaro Andreu-Bernabeu  103 Antonia San José Cáceres  104 Celso Arango  105 Covadonga M Díaz-Caneja  106 Diego Hidalgo-Mazzei  107 Eduard Vieta  108 Javier Gonzalez-Peñas  109 Lydia Fortea  110 Mara Parellada  111 Miquel A Fullana  112 Norma Verdolini  113 Eva Fárková  114 Karolina Janků  115 Mark Millan  116 Mihaela Honciuc  117 Anna Moniuszko-Malinowska  118 Igor Łoniewski  119 Jerzy Samochowiec  120 Łukasz Kiszkiel  121 Maria Marlicz  122 Paweł Sowa  123 Wojciech Marlicz  124 Georgina Spies  125 Brendon Stubbs  126 Joseph Firth  127 Sarah Sullivan  128 Asli Enez Darcin  129 Hatice Aksu  130 Nesrin Dilbaz  131 Onur Noyan  132 Momoko Kitazawa  133 Shunya Kurokawa  134 Yuki Tazawa  135 Alejandro Anselmi  136 Cecilia Cracco  137 Ana Inés Machado  138 Natalia Estrade  139 Diego De Leo  140 Jackie Curtis  141 Michael Berk  142 Philip Ward  143 Scott Teasdale  144 Simon Rosenbaum  145 Wolfgang Marx  146 Adrian Vasile Horodnic  147 Liviu Oprea  148 Ovidiu Alexinschi  149 Petru Ifteni  150 Serban Turliuc  151 Tudor Ciuhodaru  152 Alexandra Bolos  153 Valentin Matei  154 Dorien H Nieman  155 Iris Sommer  156 Jim van Os  157 Therese van Amelsvoort  158 Ching-Fang Sun  159 Ta-Wei Guu  160 Can Jiao  161 Jieting Zhang  162 Jialin Fan  163 Liye Zou  164 Xin Yu  165 Xinli Chi  166 Philippe de Timary  167 Ruud van Winke  168 Bernardo Ng  169 Edilberto Pena  170 Ramon Arellano  171 Raquel Roman  172 Thelma Sanchez  173 Larisa Movina  174 Pedro Morgado  175 Sofia Brissos  176 Oleg Aizberg  177 Anna Mosina  178 Damir Krinitski  179 James Mugisha  180 Dena Sadeghi-Bahmani  181 Masoud Sadeghi  182 Samira Hadi  183 Serge Brand  184 Antonia Errazuriz  185 Nicolas Crossley  186 Dragana Ignjatovic Ristic  187 Carlos López-Jaramillo  188 Dimitris Efthymiou  189 Praveenlal Kuttichira  190 Roy Abraham Kallivayalil  191 Afzal Javed  192 Muhammad Iqbal Afridi  193 Bawo James  194 Omonefe Joy Seb-Akahomen  195 Jess Fiedorowicz  196 Andre F Carvalho  197 Jeff Daskalakis  198 Lakshmi N Yatham  199 Lin Yang  200 Tarek Okasha  201 Aïcha Dahdouh  202 Björn Gerdle  203 Jari Tiihonen  204 Jae Il Shin  205 Jinhee Lee  206 Ahmed Mhalla  207 Lotfi Gaha  208 Takoua Brahim  209 Kuanysh Altynbekov  210 Nikolay Negay  211 Saltanat Nurmagambetova  212 Yasser Abu Jamei  213 Mark Weiser  214 Christoph U Correll  215
Affiliations

Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A)

Marco Solmi et al. J Affect Disord. .

Abstract

Background: The COVID-19 pandemic has altered daily routines and family functioning, led to closing schools, and dramatically limited social interactions worldwide. Measuring its impact on mental health of vulnerable children and adolescents is crucial.

Methods: The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT - www.coh-fit.com) is an on-line anonymous survey, available in 30 languages, involving >230 investigators from 49 countries supported by national/international professional associations. COH-FIT has thee waves (until the pandemic is declared over by the WHO, and 6-18 months plus 24-36 months after its end). In addition to adults, COH-FIT also includes adolescents (age 14-17 years), and children (age 6-13 years), recruited via non-probability/snowball and representative sampling and assessed via self-rating and parental rating. Non-modifiable/modifiable risk factors/treatment targets to inform prevention/intervention programs to promote health and prevent mental and physical illness in children and adolescents will be generated by COH-FIT. Co-primary outcomes are changes in well-being (WHO-5) and a composite psychopathology P-Score. Multiple behavioral, family, coping strategy and service utilization factors are also assessed, including functioning and quality of life.

Results: Up to June 2021, over 13,000 children and adolescents from 59 countries have participated in the COH-FIT project, with representative samples from eleven countries.

Limitations: Cross-sectional and anonymous design.

Conclusions: Evidence generated by COH-FIT will provide an international estimate of the COVID-19 effect on children's, adolescents' and families', mental and physical health, well-being, functioning and quality of life, informing the formulation of present and future evidence-based interventions and policies to minimize adverse effects of the present and future pandemics on youth.

Keywords: Adolescents; Children; Covid-19; Mental health; Pandemic; Physical health; Resilience.

PubMed Disclaimer

Conflict of interest statement

All conflict of interest statements of all authors are detailed below in supplementary Table 1.

Figures

Fig. 1
Fig. 1
COH-FIT-Adolescents and COH-FIT-Children survey flow. Legend. ASRM, Altman Self-Rating Mania Scale (Altman et al., 1997); BOCS, Brief Obsessive Compulsive Scale (Bejerot et al., 2014); BRS, Brief Resilience Scale (Smith et al., 2008); CGAS, Children's Global Assessment Scale (Shaffer et al., 1983); GAD-7, Generalized Anxiety Disorder 7-item scale (Spitzer et al., 2006); OCD, Obsessive Compulsive Disorder; PCL-5, PTSD Checklist for DSM-517; PHQ-9, Patient Health Questionnaire 9-item scale (Kroenke et al., 2001); PQ-LES-Q, Pediatric Quality of Life Enjoyment and Satisfaction Questionnaire (Endicott et al., 2006); PQ-16, Prodromal Questionnaire-1620; PTSD, Post-Traumatic Stress Disorder; SBQ-R, Suicidal Behaviors Questionnaire-Revised (Osman et al., 2001).

References

    1. Altman E.G., Hedeker D., Peterson J.L., Davis J.M. The Altman Self-Rating Mania Scale.; 1997. - PubMed
    1. Becker S.P., Breaux R., Cusick C.N., et al. Remote Learning During COVID-19: examining School Practices, Service Continuation, and Difficulties for Adolescents With and Without Attention-Deficit/Hyperactivity Disorder. J Adolesc Heal. 2020;67(6):769–777. doi: 10.1016/j.jadohealth.2020.09.002. - DOI - PMC - PubMed
    1. Bejerot S., Edman G., Anckarsäter H., et al. The Brief Obsessive-Compulsive Scale (BOCS): a self-report scale for OCD and obsessive-compulsive related disorders. Nord J Psychiatry. 2014;68(8):549–559. doi: 10.3109/08039488.2014.884631. - DOI - PMC - PubMed
    1. Blevins C.A., Weathers F.W., Davis M.T., Witte T.K., Domino J.L. The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5): development and Initial Psychometric Evaluation. J Trauma Stress. 2015;28(6):489–498. doi: 10.1002/jts.22059. - DOI - PubMed
    1. Chi X., Becker B., Yu Q., et al. Prevalence and Psychosocial Correlates of Mental Health Outcomes Among Chinese College Students During the Coronavirus Disease (COVID-19) Pandemic. Front psychiatry. 2020;11:803. doi: 10.3389/fpsyt.2020.00803. - DOI - PMC - PubMed