Fluorescent Guided Lymph Node Harvest in Laparoscopic Wilms Nephroureterectomy

Abstract

Lymph node harvest is an integral part of Wilms tumor surgery with both SIOP and COG protocols asking for more than 6 lymph nodes to best evaluate for nodal spread and a subsequent need for intensification of treatment. The majority of studies show that in both open and minimally invasive resections the median number of nodes removed is 4. Indocyanine green and near infrared fluorescence may be the key to solving this problem. In adult gynaecology, colorectal and breast cancers, ICG is used to identify sentinel nodes and facilitate nodal retrieval. This report describes its use in Wilms tumor as a technique to aid lymph node harvest.

Trial registration: ClinicalTrials.gov NCT04854018.