Is bilevel PAP more effective than CPAP in treating hypercapnic obese patients with COPD and severe OSA?
- PMID: 34608857
- PMCID: PMC8807897
- DOI: 10.5664/jcsm.9710
Is bilevel PAP more effective than CPAP in treating hypercapnic obese patients with COPD and severe OSA?
Conflict of interest statement
All authors have seen and approved this manuscript. The authors report no conflicts of interest.
Comment on
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A pilot randomized trial comparing CPAP vs bilevel PAP spontaneous mode in the treatment of hypoventilation disorder in patients with obesity and obstructive airway disease.J Clin Sleep Med. 2022 Jan 1;18(1):99-107. doi: 10.5664/jcsm.9506. J Clin Sleep Med. 2022. PMID: 34170241 Free PMC article. Clinical Trial.
References
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- Köhnlein T, Windisch W, Köhler D, et al. . Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. Lancet Respir Med. 2014; 2( 9): 698– 705. - PubMed
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- Masa JF, Mokhlesi B, Benítez I, et al. . Spanish Sleep Network. Long-term clinical effectiveness of continuous positive airway pressure therapy versus non-invasive ventilation therapy in patients with obesity hypoventilation syndrome: a multicentre, open-label, randomised controlled trial. Lancet. 2019; 393( 10182): 1721– 1732. - PubMed
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- Howard ME, Piper AJ, Stevens B, et al. . A randomised controlled trial of CPAP versus non-invasive ventilation for initial treatment of obesity hypoventilation syndrome. Thorax. 2017; 72( 5): 437– 444. - PubMed
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