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. 2021 Sep;32(9):801-807.
doi: 10.5152/tjg.2021.21229.

Analysis of Quality of Life, Depression, and Sexual Function in Patients on the Liver Transplant List

Cihan Fidan  1 , Aydıncan Akdur  2 , Mahir Kırnap  2 , Haldun Selçuk  3 , Sedat Yıldırım  2 , Gökhan Moray  2 , Mehmet Haberal  2
Affiliations

Analysis of Quality of Life, Depression, and Sexual Function in Patients on the Liver Transplant List

Cihan Fidan et al. Turk J Gastroenterol. 2021 Sep.

Abstract

Background: The only treatment in patients developing liver failure is liver transplantation. According to the Ministry of Health, the number of patients waiting for a liver transplantation is 2141, the average waiting period for liver transplantation is approximately 5 years, and 15-18% of these patients lose their life while waiting for transplantation. In these patients, limitations in daily activities and depression-anxiety are commonly found. The aim of this study was to analyze life quality, depression symptoms, and existence of sexual functional disorders of patients waiting for liver transplantation.

Methods: A total of 74 patients, who were registered in Başkent University Hospital between 2015 and 2018, were included into the study. Short Form-36, Beck Depression Inventory, and Arizona Sexual Experiences Scale were applied to 56 patients who approved study.

Results: Most of the patients were male (64.3%), and the mean age was 46 (18-64). Short Form-36 scores were low in all patients. The mean Beck Depression Inventory score of patients was found as 18.4 ± 11.3, and they were suffering from moderate depressive symptoms. According to Arizona Sexual Experiences Scale, total mean scores of males was found as 16.3 ± 5.5, and for females, it was 19.5 ± 5.3 with a statistically significant difference (P < .05). It was found that sexual dysfunction mostly had moderate to mild.

Conclusion: Depression and sexual dysfunction are common in patients with chronic liver diseases, and their life qualities deteriorate significantly. It is anticipated that evaluation of these patients in terms of psychological issues and sexual dysfunction will increase their quality of life during the organ waiting period and affect their well-being post-transplant.

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Conflict of interest statement

Conflict of Interest: The authors have no conflict of interest to declare.

Figures

Figure 1.
Figure 1.
Short Form-36 scores of females, males, and total. PF, physical functioning; RP, role physical; BP, bodily pain; GH, general health; VT, vitality; SF, social functioning; RE, role emotional; MH, mental health; PCS, physical composite score; MCS, mental composite score.
Figure 2.
Figure 2.
Arizona Sexual Experiences Scale scores. F, female; M, male.
Figure 3.
Figure 3.
Beck Depression Inventory and SF-36 scores. PF, physical functioning; RP, role physical; BP, bodily pain; GH, general health; VT, vitality; SF, social functioning; RE, role emotional; MH, mental health; PCS, physical composite score; MCS, mental composite score; SD, sexual dysfunction.
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References

    1. Aydemir O, Psikiyatrisi K-L, Kalitesi Y. Consultation-liaison psychiatry and quality of life. Turk Klin J Med Sci. 2006;47:85–88..
    1. Orr JG, Homer T, Ternent L, et al. Health related quality of life in people with advanced chronic liver disease. J Hepatol. 2014;61(5):1158–1165.. 10.1016/j.jhep.2014.06.034) - DOI - PubMed
    1. Saracino RM, Jutagir DR, Cunningham A, et al. Psychiatric comorbidity, health-related quality of life, and Mental Health Service Utilization Among Patients Awaiting Liver Transplant. J Pain Symptom Manag. 2018;56(1):44–52.. 10.1016/j.jpainsymman.2018.03.001) - DOI - PMC - PubMed
    1. T. C. Organ Transplantation Coordination Statistics of the Ministry of Health. Available at: https://organkds.saglik.gov.tr/dss/publıc/wl_liver.aspx, Accessed January 10, 2018.
    1. Rogal SS, Dew MA, Fontes P, DiMartini AF. Early treatment of depressive symptoms and long-term survival after liver transplantation. Am J Transplant. 2013;13(4):928–935.. 10.1111/ajt.12164) - DOI - PMC - PubMed