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. 2022 Jun;31(6):1621-1637.
doi: 10.1007/s11136-021-03007-9. Epub 2021 Oct 6.

Feasibility of the EQ-5D in the elderly population: a systematic review of the literature

Affiliations

Feasibility of the EQ-5D in the elderly population: a systematic review of the literature

Ole Marten et al. Qual Life Res. 2022 Jun.

Abstract

Purpose: The EQ-5D-3L and 5L are widely used generic preference-based instruments, which are psychometrically sound with the general population, but little is known about the instruments' feasibility in the elderly. Therefore, this systematic review summarises the available literature with regard to the feasibility properties of the instruments in the elderly population.

Methods: We conducted a systematic search in PubMed, PsycInfo and EuroQol databases using pre-specified vocabulary and inclusion/exclusion criteria to identify publications until November 2020. Study characteristics and outcomes referring to the feasibility of the EQ-5D-3L and 5L in the elderly were extracted, if all study participants were at least 65+ years.

Results: We identified 17 studies reporting feasibility outcomes based on four criteria: missing values, completion rates, completion time and broad qualitative statements referring to the completion. Missing values per dimension ranged from 0 to 10.7%, although being mostly below 7%. The completion rate was around 90% or better, whereas the EQ VAS rating was missing from 2.3 to 25.3% of the respondents. Only two of the included studies examined the EQ-5D-5L; 15 studies reported on the EQ-5D-3L.

Conclusion: Comparing our findings against the general population from published literature, we find that feasibility outcomes in older age groups are just below that of younger populations. Furthermore, older respondents have a higher propensity of requiring assistance or even an interviewer-based approach. Nonetheless, the reviewed literature indicates that the EQ-5D-3L still has good feasibility properties and, hence, is highly applicable in older respondents. However, further research is needed to explore feasibility properties of the EQ-5D-5L in this population.

Keywords: EQ-5D; EQ-5D-5L; Elderly; Feasibility; Health-related quality of life; Systematic review.

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Conflict of interest statement

Ole Marten and Wolfgang Greiner are members of the EuroQol Group. There are no other conflict of interest.

Figures

Fig. 1
Fig. 1
Flow chart of the literature search and study selection process

References

    1. OECD . Elderly population (indicator) OECD Publishing; 2021.
    1. United Nations (UN) World population prospects. United Nations; 2019.
    1. Kingston A, Robinson L, Booth H, Knapp M, Jagger C. Projections of multi-morbidity in the older population in England to 2035: Estimates from the population ageing and care simulation (PACSim) model. Age and Ageing. 2018;47(3):374–380. doi: 10.1093/ageing/afx201. - DOI - PMC - PubMed
    1. Salive ME. Multimorbidity in older adults. Epidemiologic Reviews. 2013;35(1):75–83. doi: 10.1093/epirev/mxs009. - DOI - PubMed
    1. Wolff JL, Starfield B, Anderson G. Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. Archives of Internal Medicine. 2002;162(20):2269–2276. doi: 10.1001/archinte.162.20.2269. - DOI - PubMed

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