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Comment
. 2021 Oct 5;33(10):1901-1903.
doi: 10.1016/j.cmet.2021.08.019.

Happy gut, happy kidneys? Restoration of gut microbiome ameliorates acute and chronic kidney disease

Samuel Mon-Wei Yu  1 , John Cijiang He  2
Affiliations
Comment

Happy gut, happy kidneys? Restoration of gut microbiome ameliorates acute and chronic kidney disease

Samuel Mon-Wei Yu et al. Cell Metab. .

Abstract

In a new study, Zhu et al. (2021) show that mitigating dysbiosis by the probiotic L. casei Zhang reduces kidney inflammation via restoring short-chain fatty acid-producing gut microbiome and nicotinamide metabolism. These findings shed light on the underlying mechanisms of probiotics in treating human kidney diseases.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Figures

Figure 1.
Figure 1.
Schematic of the kidney-and-gut axis mediating maladaptive kidney repair to kidney fibrosis
See this image and copyright information in PMC

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References

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