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Comment
. 2021 Oct 6;6(1):360.
doi: 10.1038/s41392-021-00770-6.

Context-specific chromatin remodeling activity of mSWI/SNF complexes depends on the epigenetic landscape

Godwin Sokpor  1 , Huu Phuc Nguyen  2 , Tran Tuoc  3
Affiliations
Comment

Context-specific chromatin remodeling activity of mSWI/SNF complexes depends on the epigenetic landscape

Godwin Sokpor et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Shows a schematic illustration of the mSWI/SNF complexes and their chromatin engagement. A snapshot of the dependence of the mSWI/SNF complexes on epigenetic cues in the chromatin landscape for regulating chromatin structure; hence gene expression has been depicted. Complex-specific subunits which afford modules for differentiating the three mSWI/SNF complexes are differently color coded, whereas common subunits are given the same color codes. Chromatin accessibility is regulated by histone/nucleosome signals which drive the assembly and binding of particular mSWI/SNF complexes to exert an inhibitory or activation effect on gene expression. mSWI/SNF complexes shown: cBAF canonical BAF, ncBAF non-canonical BAF, PBAF polybromo-associated BAF. Histone marks shown: ac acetylation/acylation, me methylation, p phosphorylation, ub ubiquitylation
See this image and copyright information in PMC

Comment on

References

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