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Review
. 2021 Oct 1;27(5):1344-1364.
doi: 10.1212/CON.0000000000001004.

Neuromuscular Disorders in the Intensive Care Unit

Torrey Boland Birch
Review

Neuromuscular Disorders in the Intensive Care Unit

Torrey Boland Birch. Continuum (Minneap Minn). .

Abstract

Purpose of review: This article discusses the pathophysiology, presentation, diagnosis, treatment, and prognosis of common neuromuscular disorders seen in the intensive care unit, including Guillain-Barré syndrome, myasthenia gravis, and intensive care unit-acquired weakness.

Recent findings: Guillain-Barré syndrome can have an excellent prognosis if patients are diagnosed early, appropriately treated, and monitored for complications, including respiratory failure and dysautonomia. Intensive care unit-acquired weakness increases overall mortality in patients who are critically ill, and distinguishing between critical illness myopathy and critical illness polyneuropathy may have important prognostic implications.

Summary: Neuromuscular disorders are not rare in the intensive care unit setting, and precise identification and treatment of these conditions can greatly impact long-term outcomes.

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