An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.
The site is secure.
The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
1 Department of Gastroenterology and Hepatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom. Electronic address: g.tun@nhs.net.
2 Department of Gastroenterology and Hepatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
1 Department of Gastroenterology and Hepatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom. Electronic address: g.tun@nhs.net.
2 Department of Gastroenterology and Hepatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Conflict of interest The authors declare no conflicts of interest that pertain to this work. Please refer to the accompanying ICMJE disclosure forms for further details.
Figures
Fig. 1
Histological findings and biochemical findings.…
Fig. 1
Histological findings and biochemical findings. H&E-stained section of liver biopsy indicates acute hepatitis.…
Fig. 1
Histological findings and biochemical findings. H&E-stained section of liver biopsy indicates acute hepatitis. (A) The parenchymal hepatocytes are arranged into rosette forms (marked with arrows) with cholestasis. (B) BN from hepatocyte loss, some by apoptosis (arrow). (C) Diagram showing trend of bilirubin and ALT following Moderna vaccine dose 1 and 2 with response to prednisolone. ALT, alanine aminotransferase; BN, bridging necrosis. (This figure appears in color on the web.)
Bril F., Al Diffalha S., Dean M., Fettig D.M., et al. Autoimmune hepatitis developing after coronavirus disease 2019 (COVID-19) vaccine: causality or casualty? J Hepatol. 2021;75(1):222–224.
-
PMC
-
PubMed
Rocco A., Sgamato C., Compare D., Nardone G., et al. Autoimmune hepatitis following SARS-CoV-2 vaccine: may not be a casualty. J Hepatol. 2021;75(3):728–729.
-
PMC
-
PubMed
Londono M.C., Gratacos-Gines J., Saez-Penataro J. Another case of autoimmune hepatitis after SARS-CoV-2 vaccination. Still casualty? J Hepatol. 2021 doi: 10.1016/j.jhep.2021.06.004.
-
DOI
-
PMC
-
PubMed
Ghielmetti M., Schaufelberger H.D., Mieli-Vergani G., Cerny A., et al. Acute autoimmune-like hepatitis with atypical anti-mitochondrial antibody after mRNA COVID-19 vaccination: a novel clinical entity? J Autoimmun. 2021;123:102706.
-
PMC
-
PubMed
McShane C., Kiat C., Rigby J., Crosbie O., et al. The mRNA COVID-19 vaccine - a rare trigger of Autoimmune Hepatitis? J Hepatol. 2021 S0168-8278(21)01896-1.
-
PMC
-
PubMed