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. 2022 Feb;61(2):111-114.e3.
doi: 10.1016/j.jaac.2021.09.415. Epub 2021 Oct 4.

Does Pro Re Nata Oral Medication Shorten Outburst Duration in Children?

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Does Pro Re Nata Oral Medication Shorten Outburst Duration in Children?

Gabrielle A Carlson et al. J Am Acad Child Adolesc Psychiatry. 2022 Feb.

Abstract

We report a prospective, naturalistic, institutional review board-approved study of 104 children ages 5-12 in a psychiatric hospital, of whom 59 were treated with oral PRN medications per parent/guardian-consent, given at nursing discretion, with physicians informed subsequently, and intramuscular STAT medication and/or seclusion/restraint/holds (S/R/H) in dangerous situations when oral medication failed. Intramuscular STAT medication and/or S/R/H were ordered by physicians with parents informed subsequently. The outcome of interest was the duration of the outburst and whether this differed by PRN medication.

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