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. 2022 Jan;42(1):199-202.
doi: 10.1007/s10875-021-01138-9. Epub 2021 Oct 7.

Abnormal Results of Newborn Screening for SCID After Azathioprine Exposure In Utero: Benefit of TPMT Genotyping in Both Mother and Child

Maartje Blom  1 , Ingrid Pico-Knijnenburg  1 , Joris M van Montfrans  2 , Robbert G M Bredius  3 , Mirjam van der Burg  1 , Jesse J Swen  4 , Dagmar Berghuis  5
Affiliations

Abnormal Results of Newborn Screening for SCID After Azathioprine Exposure In Utero: Benefit of TPMT Genotyping in Both Mother and Child

Maartje Blom et al. J Clin Immunol. 2022 Jan.
No abstract available

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References

    1. Thomas C, et al. A severe neonatal lymphopenia associated with administration of azathioprine to the mother in a context of Crohn’s disease. J Crohn’s Colitis. 2017;12(2):258–61. - DOI
    1. Kuo CY, et al. Profound T-cell lymphopenia associated with prenatal exposure to purine antagonists detected by TREC newborn screening. J Allergy Clin Immunol Pract. 2017;5(1):198–200. - DOI
    1. Barbaro M, et al. Newborn screening for severe primary immunodeficiency diseases in Sweden-a 2-year pilot TREC and KREC screening study. J Clin Immunol. 2017;37(1):51–60. - DOI
    1. Amatuni GS, et al. Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California, 2010–2017. Pediatrics. 2019;143(2):e20182300.
    1. Thomas C, et al. Clinical and economic aspects of newborn screening for severe combined immunodeficiency: DEPISTREC study results. Clin Immunol. 2019;202:33–9. - DOI

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