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. 2021 Dec 7;37(23):4562-4563.
doi: 10.1093/bioinformatics/btab698.

iNucs: inter-nucleosome interactions

Mehrdad Oveisi  1 , Manu Shukla  2 , Nogayhan Seymen  1 , Masae Ohno  3   4 , Yuichi Taniguchi  3   4 , Sunil Nahata  5 , Remco Loos  6 , Ghulam J Mufti  1 , Robin C Allshire  2 , Stefan Dimitrov  5   7 , Mohammad M Karimi  1
Affiliations

iNucs: inter-nucleosome interactions

Mehrdad Oveisi et al. Bioinformatics. .

Abstract

Motivation: Deciphering nucleosome-nucleosome interactions is an important step toward mesoscale description of chromatin organization but computational tools to perform such analyses are not publicly available.

Results: We developed iNucs, a user-friendly and efficient Python-based bioinformatics tool to compute and visualize nucleosome-resolved interactions using standard pairs format input generated from pairtools.

Availabilityand implementation: https://github.com/Karimi-Lab/inucs/.

Supplementary information: Supplementary data are available at Bioinformatics online.

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Figures

Fig. 1.
Fig. 1.
iNUcs overview and performance. (A) Schematics of input data requirements, analysis modules and generated output. (B) Table showing input data, complexity, computational resource and respective times required to perform the analysis
See this image and copyright information in PMC

References

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    1. Ohno M. et al. (2019) Sub-nucleosomal genome structure reveals distinct nucleosome folding motifs. Cell, 176, 520–534.e25. - PubMed
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