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. 2021 Oct 8;21(1):141.
doi: 10.1186/s12894-021-00905-5.

Risk factors of kidney stone disease: a cross-sectional study in the southeast of Iran

Parvin Khalili  1 , Zahra Jamali  2 , Tabandeh Sadeghi  3 , Ali Esmaeili-Nadimi  2 , Maryam Mohamadi  4 , Amir Moghadam-Ahmadi  5 , Fatemeh Ayoobi  6 , Alireza Nazari  2
Affiliations

Risk factors of kidney stone disease: a cross-sectional study in the southeast of Iran

Parvin Khalili et al. BMC Urol. .

Abstract

Background: The prevalence of kidney stones in the world is increasing and environmental factors seem to play a major role in this issue. The aim of the present study was to investigate the prevalence of risk factors of kidney stones in the adult population of Rafsanjan city based on the data of the Rafsanjan Cohort Study (RCS).

Methods: In the baseline phase of this study, 10,000 people aged 35 to 70 years are enrolled in the RCS, as one of the prospective epidemiological research studies in Iran. From this population, 9932 participants completed related demographic questionnaires as well as reported a history of diabetes mellitus, kidney stone, and hypertension diseases. The obtained data were analyzed using univariable and multivariable logistics regression.

Results: According to the obtained results, 46.54% of the studied population were male and 53.46% were female. The mean age of the participants was 49.94 ± 9.56 years. 2392 people accounting for 24.08% of the population had kidney stones. After adjustment of the variables, six variables of gender, WSI, no consumption of purified water, BMI, and history of hypertension and diabetes were found to be significant related factors of kidney stone disease.

Conclusions: Gender, hypertension, obesity, diabetes, and personal habits like alcohol consumption, opium use and, cigarette smoking are effective in the development of kidney stones. So, by identifying the susceptible patients and teaching them, the burden of the disease on society and the individual can be reduced. The results of this study are helpful to health care providers for preventive planning for kidney stone disease.

Keywords: Kidney stone; Prospective epidemiological research studies in Iran (PERSIAN); Risk factors.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
ROC curve of the related factors for the identification of kidney stone
See this image and copyright information in PMC

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