Published Erratum
doi: 10.1038/s41591-021-01569-2.
Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Evdoxia Kyriazopoulou
1
, Garyfallia Poulakou
2
, Haralampos Milionis
3
, Simeon Metallidis
4
, Georgios Adamis
5
, Konstantinos Tsiakos
6
, Archontoula Fragkou
7
, Aggeliki Rapti
6
, Christina Damoulari
1
, Massimo Fantoni
8
, Ioannis Kalomenidis
9
, Georgios Chrysos
10
, Andrea Angheben
11
, Ilias Kainis
12
, Zoi Alexiou
13
, Francesco Castelli
14
, Francesco Saverio Serino
15
, Maria Tsilika
1
, Petros Bakakos
16
, Emanuele Nicastri
17
, Vassiliki Tzavara
18
, Evangelos Kostis
19
, Lorenzo Dagna
20
, Panagiotis Koufargyris
1
, Katerina Dimakou
21
, Spyridon Savvanis
7
, Glykeria Tzatzagou
22
, Maria Chini
23
, Giulio Cavalli
20
, Matteo Bassetti
24
, Konstantina Katrini
1
, Vasileios Kotsis
25
, George Tsoukalas
26
, Carlo Selmi
27
, Ioannis Bliziotis
28
, Michael Samarkos
29
, Michael Doumas
30
, Sofia Ktena
1
, Aikaterini Masgala
31
, Ilias Papanikolaou
32
, Maria Kosmidou
3
, Dimitra-Melia Myrodia
2
, Aikaterini Argyraki
33
, Chiara Simona Cardellino
11
, Katerina Koliakou
34
, Eleni-Ioanna Katsigianni
34
, Vassiliki Rapti
2
, Efthymia Giannitsioti
10
, Antonella Cingolani
8
, Styliani Micha
34
, Karolina Akinosoglou
35
, Orestis Liatsis-Douvitsas
34
, Styliani Symbardi
36
, Nikolaos Gatselis
37
, Maria Mouktaroudi
1
34
, Giuseppe Ippolito
17
, Eleni Florou
34
, Antigone Kotsaki
1
, Mihai G Netea
38
39
, Jesper Eugen-Olsen
40
, Miltiades Kyprianou
34
, Periklis Panagopoulos
41
, George N Dalekos
37
, Evangelos J Giamarellos-Bourboulis
42
43
Affiliations
Affiliations
- 1 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 2 3rd Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 3 1st Department of Internal Medicine, University of Ioannina, Medical School, Ioannina, Greece.
- 4 1st Department of Internal Medicine, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
- 5 1st Department of Internal Medicine, G. Gennimatas General Hospital of Athens, Athens, Greece.
- 6 2nd Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 7 Department of Internal Medicine, Elpis General Hospital, Athens, Greece.
- 8 Dipartimento Scienze di Laboratorio e Infettivologiche - Fondazione Policlinico Gemelli IRCCS, Roma, Italy.
- 9 1st Department of Critical Care and Pulmonary Medicine, Medical School, National and Kapodistrian University of Athens, Evangelismos General Hospital, Athens, Greece.
- 10 2nd Department of Internal Medicine, Tzaneio General Hospital of Piraeus, Athens, Greece.
- 11 Department of Infectious Tropical Diseases and Microbiology, IRCSS Sacro Cuore Hospital, Negrar, Verona, Italy.
- 12 10th Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases of Athens, Athens, Greece.
- 13 2nd Department of Internal Medicine, Thriasio General Hospital of Eleusis, Athens, Greece.
- 14 Spedali Civili, Brescia ASST Spedali Civili Hospital, University of Brescia, Brescia, Italy.
- 15 Department of Internal Medicine, Hospital of Jesolo, Jesolo, Italy.
- 16 1st Department of Chest Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 17 Department of Internal Medicine, Spallanzani Institute of Rome, Rome, Italy.
- 18 1st Department of Internal Medicine, Korgialeneion-Benakeion General Hospital, Athens, Greece.
- 19 Department of Therapeutics, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 20 Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS Ospedale San Raffaele & Vita-Salute San Raffaele University, Milan, Italy.
- 21 5th Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 22 1st Department of Internal Medicine, Papageorgiou General Hospital of Thessaloniki, Thessaloniki, Greece.
- 23 3rd Department of Internal Medicine and Infectious Diseases Unit, Korgialeneion-Benakeion General Hospital, Athens, Greece.
- 24 Infectious Diseases Clinic, Ospedale Policlinico San Martino IRCCS and Department of Health Sciences, University of Genova, Genova, Italy.
- 25 3rd Department of Internal Medicine, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
- 26 4th Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 27 Department of Biomedical Sciences, Humanitas University, Milan, Italy & IRCCS Humanitas Research Hospital, Milan, Italy.
- 28 1st Department of Internal Medicine, Asklepieio General Hospital of Voula, Athens, Greece.
- 29 1st Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 30 2nd Department of Propedeutic Medicine, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
- 31 2nd Department of Internal Medicine, Konstantopouleio General Hospital, Athens, Greece.
- 32 Department of Pulmonary Medicine, General Hospital of Kerkyra, Corfu, Greece.
- 33 Department of Internal Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 34 Hellenic Institute for the Study of Sepsis, Athens, Greece.
- 35 Department of Internal Medicine, University of Patras, Rion, Greece.
- 36 1st Department of Internal Medicine, Thriasio General Hospital of Eleusis, Athens, Greece.
- 37 Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece.
- 38 Department of Internal Medicine and Center for Infectious Diseases, Radboud University, Nijmegen, The Netherlands.
- 39 Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.
- 40 Department of Clinical Research, Copenhagen University Hospital, Amager and Hvidovre, Denmark.
- 41 2nd Department of Internal Medicine, Democritus University of Thrace, Medical School, Alexandroupolis, Greece.
- 42 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece. egiamarel@med.uoa.gr.
- 43 Hellenic Institute for the Study of Sepsis, Athens, Greece. egiamarel@med.uoa.gr.
- PMID: 34625750
- PMCID: PMC8500253
- DOI: 10.1038/s41591-021-01569-2
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Published Erratum
Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Evdoxia Kyriazopoulou et al.
Nat Med.
2021 Oct.
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Format
doi: 10.1038/s41591-021-01569-2.
Authors
Evdoxia Kyriazopoulou
1
, Garyfallia Poulakou
2
, Haralampos Milionis
3
, Simeon Metallidis
4
, Georgios Adamis
5
, Konstantinos Tsiakos
6
, Archontoula Fragkou
7
, Aggeliki Rapti
6
, Christina Damoulari
1
, Massimo Fantoni
8
, Ioannis Kalomenidis
9
, Georgios Chrysos
10
, Andrea Angheben
11
, Ilias Kainis
12
, Zoi Alexiou
13
, Francesco Castelli
14
, Francesco Saverio Serino
15
, Maria Tsilika
1
, Petros Bakakos
16
, Emanuele Nicastri
17
, Vassiliki Tzavara
18
, Evangelos Kostis
19
, Lorenzo Dagna
20
, Panagiotis Koufargyris
1
, Katerina Dimakou
21
, Spyridon Savvanis
7
, Glykeria Tzatzagou
22
, Maria Chini
23
, Giulio Cavalli
20
, Matteo Bassetti
24
, Konstantina Katrini
1
, Vasileios Kotsis
25
, George Tsoukalas
26
, Carlo Selmi
27
, Ioannis Bliziotis
28
, Michael Samarkos
29
, Michael Doumas
30
, Sofia Ktena
1
, Aikaterini Masgala
31
, Ilias Papanikolaou
32
, Maria Kosmidou
3
, Dimitra-Melia Myrodia
2
, Aikaterini Argyraki
33
, Chiara Simona Cardellino
11
, Katerina Koliakou
34
, Eleni-Ioanna Katsigianni
34
, Vassiliki Rapti
2
, Efthymia Giannitsioti
10
, Antonella Cingolani
8
, Styliani Micha
34
, Karolina Akinosoglou
35
, Orestis Liatsis-Douvitsas
34
, Styliani Symbardi
36
, Nikolaos Gatselis
37
, Maria Mouktaroudi
1
34
, Giuseppe Ippolito
17
, Eleni Florou
34
, Antigone Kotsaki
1
, Mihai G Netea
38
39
, Jesper Eugen-Olsen
40
, Miltiades Kyprianou
34
, Periklis Panagopoulos
41
, George N Dalekos
37
, Evangelos J Giamarellos-Bourboulis
42
43
Affiliations
- 1 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 2 3rd Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 3 1st Department of Internal Medicine, University of Ioannina, Medical School, Ioannina, Greece.
- 4 1st Department of Internal Medicine, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
- 5 1st Department of Internal Medicine, G. Gennimatas General Hospital of Athens, Athens, Greece.
- 6 2nd Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 7 Department of Internal Medicine, Elpis General Hospital, Athens, Greece.
- 8 Dipartimento Scienze di Laboratorio e Infettivologiche - Fondazione Policlinico Gemelli IRCCS, Roma, Italy.
- 9 1st Department of Critical Care and Pulmonary Medicine, Medical School, National and Kapodistrian University of Athens, Evangelismos General Hospital, Athens, Greece.
- 10 2nd Department of Internal Medicine, Tzaneio General Hospital of Piraeus, Athens, Greece.
- 11 Department of Infectious Tropical Diseases and Microbiology, IRCSS Sacro Cuore Hospital, Negrar, Verona, Italy.
- 12 10th Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases of Athens, Athens, Greece.
- 13 2nd Department of Internal Medicine, Thriasio General Hospital of Eleusis, Athens, Greece.
- 14 Spedali Civili, Brescia ASST Spedali Civili Hospital, University of Brescia, Brescia, Italy.
- 15 Department of Internal Medicine, Hospital of Jesolo, Jesolo, Italy.
- 16 1st Department of Chest Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 17 Department of Internal Medicine, Spallanzani Institute of Rome, Rome, Italy.
- 18 1st Department of Internal Medicine, Korgialeneion-Benakeion General Hospital, Athens, Greece.
- 19 Department of Therapeutics, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 20 Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS Ospedale San Raffaele & Vita-Salute San Raffaele University, Milan, Italy.
- 21 5th Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 22 1st Department of Internal Medicine, Papageorgiou General Hospital of Thessaloniki, Thessaloniki, Greece.
- 23 3rd Department of Internal Medicine and Infectious Diseases Unit, Korgialeneion-Benakeion General Hospital, Athens, Greece.
- 24 Infectious Diseases Clinic, Ospedale Policlinico San Martino IRCCS and Department of Health Sciences, University of Genova, Genova, Italy.
- 25 3rd Department of Internal Medicine, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
- 26 4th Department of Pulmonary Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 27 Department of Biomedical Sciences, Humanitas University, Milan, Italy & IRCCS Humanitas Research Hospital, Milan, Italy.
- 28 1st Department of Internal Medicine, Asklepieio General Hospital of Voula, Athens, Greece.
- 29 1st Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
- 30 2nd Department of Propedeutic Medicine, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
- 31 2nd Department of Internal Medicine, Konstantopouleio General Hospital, Athens, Greece.
- 32 Department of Pulmonary Medicine, General Hospital of Kerkyra, Corfu, Greece.
- 33 Department of Internal Medicine, Sotiria General Hospital of Chest Diseases, Athens, Greece.
- 34 Hellenic Institute for the Study of Sepsis, Athens, Greece.
- 35 Department of Internal Medicine, University of Patras, Rion, Greece.
- 36 1st Department of Internal Medicine, Thriasio General Hospital of Eleusis, Athens, Greece.
- 37 Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece.
- 38 Department of Internal Medicine and Center for Infectious Diseases, Radboud University, Nijmegen, The Netherlands.
- 39 Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.
- 40 Department of Clinical Research, Copenhagen University Hospital, Amager and Hvidovre, Denmark.
- 41 2nd Department of Internal Medicine, Democritus University of Thrace, Medical School, Alexandroupolis, Greece.
- 42 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece. egiamarel@med.uoa.gr.
- 43 Hellenic Institute for the Study of Sepsis, Athens, Greece. egiamarel@med.uoa.gr.
- PMID: 34625750
- PMCID: PMC8500253
- DOI: 10.1038/s41591-021-01569-2
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Erratum for
-
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial.Kyriazopoulou E, Poulakou G, Milionis H, Metallidis S, Adamis G, Tsiakos K, Fragkou A, Rapti A, Damoulari C, Fantoni M, Kalomenidis I, Chrysos G, Angheben A, Kainis I, Alexiou Z, Castelli F, Serino FS, Tsilika M, Bakakos P, Nicastri E, Tzavara V, Kostis E, Dagna L, Koufargyris P, Dimakou K, Savvanis S, Tzatzagou G, Chini M, Cavalli G, Bassetti M, Katrini K, Kotsis V, Tsoukalas G, Selmi C, Bliziotis I, Samarkos M, Doumas M, Ktena S, Masgala A, Papanikolaou I, Kosmidou M, Myrodia DM, Argyraki A, Cardellino CS, Koliakou K, Katsigianni EI, Rapti V, Giannitsioti E, Cingolani A, Micha S, Akinosoglou K, Liatsis-Douvitsas O, Symbardi S, Gatselis N, Mouktaroudi M, Ippolito G, Florou E, Kotsaki A, Netea MG, Eugen-Olsen J, Kyprianou M, Panagopoulos P, Dalekos GN, Giamarellos-Bourboulis EJ. Kyriazopoulou E, et al. Nat Med. 2021 Oct;27(10):1752-1760. doi: 10.1038/s41591-021-01499-z. Epub 2021 Sep 3. Nat Med. 2021. PMID: 34480127 Free PMC article. Clinical Trial.
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