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Comment
. 2021 Oct 9;398(10308):1304.
doi: 10.1016/S0140-6736(21)01909-7.

Age-adjusted D-dimer cutoffs to guide anticoagulation in COVID-19 - Authors' reply

Renato D Lopes  1 , Pedro Gabriel Melo de Barros E Silva  2 , Remo H M Furtado  3 , John H Alexander  4 , Otavio Berwanger  3
Affiliations
Comment

Age-adjusted D-dimer cutoffs to guide anticoagulation in COVID-19 - Authors' reply

Renato D Lopes et al. Lancet. .
No abstract available

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Comment on

  • Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.
    Lopes RD, de Barros E Silva PGM, Furtado RHM, Macedo AVS, Bronhara B, Damiani LP, Barbosa LM, de Aveiro Morata J, Ramacciotti E, de Aquino Martins P, de Oliveira AL, Nunes VS, Ritt LEF, Rocha AT, Tramujas L, Santos SV, Diaz DRA, Viana LS, Melro LMG, de Alcântara Chaud MS, Figueiredo EL, Neuenschwander FC, Dracoulakis MDA, Lima RGSD, de Souza Dantas VC, Fernandes ACS, Gebara OCE, Hernandes ME, Queiroz DAR, Veiga VC, Canesin MF, de Faria LM, Feitosa-Filho GS, Gazzana MB, Liporace IL, de Oliveira Twardowsky A, Maia LN, Machado FR, de Matos Soeiro A, Conceição-Souza GE, Armaganijan L, Guimarães PO, Rosa RG, Azevedo LCP, Alexander JH, Avezum A, Cavalcanti AB, Berwanger O; ACTION Coalition COVID-19 Brazil IV Investigators. Lopes RD, et al. Lancet. 2021 Jun 12;397(10291):2253-2263. doi: 10.1016/S0140-6736(21)01203-4. Epub 2021 Jun 4. Lancet. 2021. PMID: 34097856 Free PMC article. Clinical Trial.

References

    1. Lopes RD, de Barros e Silva PGM, Furtado RHM, et al. Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial. Lancet. 2021;397:2253–2263. - PMC - PubMed
    1. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18:844–847. - PMC - PubMed
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    1. The REMAP-CAP, ACTIV-4a, and ATTACC Investigators Therapeutic anticoagulation with heparin in critically ill patients with COVID-19. N Engl J Med. 2021 doi: 10.1056/NEJMoa2103417. published online Aug 4. - DOI - PMC - PubMed
    1. The ATTACC, ACTIV-4a, and REMAP-CAP Investigators Therapeutic anticoagulation with heparin in noncritically ill patients with COVID-19. N Engl J Med. 2021 doi: 10.1056/NEJMoa2105911. published online Aug 4. - DOI - PMC - PubMed

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