Editorial: Metalloenzymes: Potential Drug Targets
- PMID: 34630115
- PMCID: PMC8497783
- DOI: 10.3389/fphar.2021.746925
Editorial: Metalloenzymes: Potential Drug Targets
Keywords: ecto-5′-nucleotidase; inhibitors; metalloenzymes; nucleoside triphosphate diphosphohydrolases; nucleotide pyrophosphatase/phosphodiesterases.
Conflict of interest statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Comment on
- Editorial on the Research Topic Metalloenzymes: Potential Drug Targets
References
-
- Abbas S., Zaib S., Rahman S. U., Ali S., Hameed S., Tahir M. N., et al. (2019b). Carbonic Anhydrase Inhibitory Potential of 1,2,4-Triazole-3-Thione Derivatives of Flurbiprofen, Ibuprofen and 4-Tert-Butylbenzoic Hydrazide: Design, Synthesis, Characterization, Biochemical Evaluation, Molecular Docking and Dynamic Simulation Studies. Med. Chem. 15 (3), 298–310. 10.2174/1573406414666181012165156 - DOI - PubMed
-
- Abbas S., Nasir H. H., Zaib S., Ali S., Mahmood T., Ayub K., et al. (2018). Carbonic Anhydrase Inhibition of Schiff Base Derivative of Imino-Methyl-Naphthalen-2-Ol: Synthesis, Structure Elucidation, Molecular Docking, Dynamic Simulation and Density Functional Theory Calculations. J. Mol. Struct. 1156, 193–200. 10.1016/j.molstruc.2017.11.086 - DOI
-
- Afzal S., Al-Rashida M., Hameed A., Pelletier J., Sévigny J., Iqbal J. (2021). Synthesis, In-Vitro Evaluation and Molecular Docking Studies of Oxoindolin Phenylhydrazine Carboxamides as Potent and Selective Inhibitors of Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase). Bioorg. Chem. 112, 104957. 10.1016/j.bioorg.2021.104957 - DOI - PubMed
-
- Afzal S., Zaib S., Jafari B., Langer P., Lecka J., Sévigny J., et al. (2020). Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7- Trifluoromethyl-Thiadiazolopyrimidones Scaffold. Med. Chem. 16 (5), 689–702. 10.2174/1573406415666190614095821 - DOI - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Research Materials