Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Oct 4;9(10):e04904.
doi: 10.1002/ccr3.4904. eCollection 2021 Oct.

Ten years of battle with multiple recurrences of pediatric skull base chondrosarcoma: A case report

Affiliations
Case Reports

Ten years of battle with multiple recurrences of pediatric skull base chondrosarcoma: A case report

Mona Ariamanesh et al. Clin Case Rep. .

Abstract

In children and adolescents presenting with skull base sarcoma, treatment strategies will face challenging decisions due to the unique chemoresistant pathologies, limitations imposed by the not-yet fully mature anatomical structures, and the small surgical site.

Keywords: chondrosarcoma; proptosis; skull base.

PubMed Disclaimer

Conflict of interest statement

Authors declare that they have no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Microscopic tumor morphology in favor of a diagnosis of low‐grade chondrosarcoma. (green arrow: binucleation of chondrocytes, red arrow: large, highly atypical chondrocyte) (Left: Low Power Field, Right: High Power Field)
FIGURE 2
FIGURE 2
(A) Initial CT imaging indicating the diagnosis of skull base tumor. (B) Post‐surgical changes and complete excision demonstrated in the first post‐surgical CT imaging. (C) Final MRI imaging indicating a large heterogeneous tumoral mass which remained stable after radiation therapy

References

    1. Evans P, Montgomery PQ, Gullane PJ. Principles and Practice of Head and Neck Surgery and Oncology. CRC Press; 2009.
    1. Kobayashi K, Matsumoto F, Miyakita Y, et al. Impact of surgical margin in skull base surgery for head and neck sarcomas. J Neurol Surg B Skull Base. 2018;79(5):437‐444. - PMC - PubMed
    1. Hepel JT, Kinsella TJ. Osteosarcoma and Other Primary Tumors of Bone, Perez & Brady's Principles and Practice of Radiation Oncology, 7th ed; Philadelphia, US: Wolters Kluwer; 2019.
    1. Veth R, Schreuder B, van Beem H, et al. Cryosurgery in aggressive, benign, and low‐grade malignant bone tumours. Lancet Oncol. 2005;6(1):25‐34. - PubMed
    1. Leerapun T, Hugate RR, Inwards CY, et al. Surgical management of conventional grade I chondrosarcoma of long bones. Clin Orthop Relat Res. 2007;463:166‐172. - PubMed

Publication types

LinkOut - more resources