Pyrazolone drugs and agranulocytosis

Abstract

Ever since mass consumption of chemically pure drugs started at the beginning of this century, cases of agranulocytosis have been reported in the literature. These were very soon seen as being causally related to drug use. The present paper discusses the clinical symptoms of the disease, the possibilities of its treatment, and the obvious connections between the use of pyrazolone drugs and the occurrence of agranulocytosis.