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Review
. 2021 Oct 10;11(1):37.
doi: 10.1186/s12348-021-00267-x.

Intraocular therapy in noninfectious uveitis

Rocco Luigi Modugno  1 , Ilaria Testi  2 , Carlos Pavesio  3   4
Affiliations
Review

Intraocular therapy in noninfectious uveitis

Rocco Luigi Modugno et al. J Ophthalmic Inflamm Infect. .

Abstract

Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics.

Keywords: Anti-tumor necrosis factor (TNF) α; Anti-vascular endothelial growth factor (VEGF); Biologics; Corticosteroids; Immunosuppressive agents; Intravitreal; Local therapy; Methotrexate; Non-infectious uveitis.

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Conflict of interest statement

None.

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