Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Dec;62(12):3146-3147.
doi: 10.1111/epi.17096. Epub 2021 Oct 11.

Is the crystal ball broken? Another external validation of the post-withdrawal seizure-relapse prediction model

Affiliations
Comment

Is the crystal ball broken? Another external validation of the post-withdrawal seizure-relapse prediction model

Samuel W Terman et al. Epilepsia. 2021 Dec.
No abstract available

Keywords: antiseizure medication withdrawal; epilepsy; predictive models.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest

The authors report no conflicts of interest. We confirm that we have read the Journal’s position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.

Comment in

Comment on

References

    1. Contento M, Bertaccini B, Biggi M, Magliani M, Failli Y, Rosati E, et al. Prediction of seizure recurrence risk following discontinuation of antiepileptic drugs. Epilepsia. 2021; (July):1–12. - PMC - PubMed
    1. Lamberink HJ, Otte WM, Geerts AT, Pavlovic M, Ramos-lizana J, Marson AG, et al. Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis. Lancet Neurol. 2017; 16:523–31. - PubMed
    1. Lin J, Ding S, Li X, Hua Y, Wang X, He R, et al. External validation and comparison of two prediction models for seizure recurrence after the withdrawal of antiepileptic drugs in adult patients. Epilepsia. 2019; :1–10. - PubMed
    1. Medical Research Council. Randomised study of antiepileptic drug withdrawal in patients in remission. Lancet. 1991; 337(May):1175–80. - PubMed
    1. S shan Chu, Tan G, Wang X ping, Liu L. Validation of the predictive model for seizure recurrence after withdrawal of antiepileptic drugs. Epilepsy Behav. 2021; (114):106987. - PubMed

Substances