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. 2022 Jan;41(1):313-322.
doi: 10.1002/nau.24822. Epub 2021 Oct 11.

Adjustable continence therapy (ACT®) balloons to treat neurogenic and non-neurogenic female urinary incontinence

Amélie Demeestere  1 , Marie-Liesse de Guerry  1 , Christophe Bergot  2 , Astrid de Hauteclocque  3 , Juliette Hascoet  4 , Xavier Gamé  5 , Anne-Sophie Bajeot  4 , Benoit Peyronnet  4 , Grégoire Capon  3 , Marie-Aimée Perrouin-Verbe  2 , Xavier Biardeau  1
Affiliations

Adjustable continence therapy (ACT®) balloons to treat neurogenic and non-neurogenic female urinary incontinence

Amélie Demeestere et al. Neurourol Urodyn. 2022 Jan.

Abstract

Aims: To compare efficacy and safety between neurogenic and non-neurogenic women after adjustable continence therapy (ACT®) balloons implantation to treat stress urinary incontinence (SUI) due to intrinsic sphincter deficiency.

Methods: In the present retrospective multicentric study, all neurogenic and non-neurogenic women implanted with ACT® balloons between 2000 and 2018 were considered for inclusion. Efficacy was compared 1 year after implantation, and women were allocated in three different groups as follows. Success: maximum 1 pad per day and patient's impression of improvement assessed using a numeral rating scale (NRS) ≥8/10. Improvement: decrease of daily pad use and/or NRS ≥5/10. Failure: increase or stability of daily pad use or NRS <5/10. Overall surgical complications and explantations were compared 1 year after implantation.

Results: Among the 277 included women, 51 presented with a neurologic underlying disease. Mean age at implantation was 68.5 years. There was no significant difference in efficacy between neurogenic and non-neurogenic women with a success rate of 39.2% and 36.3%, respectively (p = 0.69). Similarly, improvement rate was reported to be 31.4% and 33.6%, in neurogenic and non-neurogenic women, respectively (p = 0.92). The overall surgical complications rate (24% vs. 34.5%, p = 0.15) and the explantation rate (19.6% vs. 28.8%, p = 0.18) were not significantly different.

Conclusion: ACT balloons may be proposed to treat mixed or SUI in females with ISD. Efficacy and safety profiles appear to be similar in both neurogenic and non-neurogenic patients.

Keywords: compression device; efficacy; intrinsic sphincter deficiency; safety; stress urinary incontinence.

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References

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