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Comment
. 2021 Oct 12:10:e73193.
doi: 10.7554/eLife.73193.

What's the use?

Jason M Fletcher  1   2   3 , Yuchang Wu  3   4 , Qiongshi Lu  3   4
Affiliations
Comment

What's the use?

Jason M Fletcher et al. Elife. .

Abstract

A theoretical framework predicts that using polygenic screening to select embryos against traits that depend on many genes has few benefits.

Keywords: embryo; genetics; genomics; human; in vitro fertilization; polygenic risk scores; preimplantation genetic testing.

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Conflict of interest statement

JF, YW, QL No competing interests declared

Comment on

References

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    1. Chen J, You J, Zhao Z, Ni Z, Huang K, Wu Y, Fletcher J, Lu Q. Gamete simulation improves polygenic transmission disequilibrium analysis. bioRxiv. 2020 doi: 10.1101/2020.10.26.355602. - DOI
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