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. 2022 Mar;32(3):182-185.
doi: 10.1016/j.tcb.2021.09.004. Epub 2021 Oct 8.

Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis

Elena Lavdovskaia  1 , Hauke S Hillen  2 , Ricarda Richter-Dennerlein  3
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Free article

Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis

Elena Lavdovskaia et al. Trends Cell Biol. 2022 Mar.
Free article

Abstract

Final maturation steps during ribosome biogenesis require the assistance of assembly and quality control factors to ensure the folding of rRNA and proteins into a functional translation machinery. Here we integrate several recent structural snapshots of native large ribosomal subunit intermediates into the complex pathway of mitochondrial ribosome assembly.

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Declaration of interests The authors have no interests to declare.

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