Malaria vaccine roller coaster
- PMID: 34635830
- PMCID: PMC7613539
- DOI: 10.1038/s41564-021-00982-0
Malaria vaccine roller coaster
Abstract
A promising vaccine fails to provide durable protection against infection and clinical malaria in infants, a key malaria vaccine target population, in a phase 2b clinical trial. The need for a highly effective vaccine against malaria remains as urgent as ever.
Conflict of interest statement
The authors declare no competing interests.
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Comment on
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Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial.Nat Med. 2021 Sep;27(9):1636-1645. doi: 10.1038/s41591-021-01470-y. Epub 2021 Sep 13. Nat Med. 2021. PMID: 34518679 Clinical Trial.
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