Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Dec;17(12):788-789.
doi: 10.1038/s41581-021-00499-z. Epub 2021 Oct 11.

COVID-19 vaccination in patients receiving dialysis

Affiliations

COVID-19 vaccination in patients receiving dialysis

Benjamin Wilde et al. Nat Rev Nephrol. 2021 Dec.

Abstract

Patients receiving dialysis are at high risk of contracting SARS-CoV-2 and developing severe COVID-19. Established SARS-CoV-2 vaccination schemes might lack efficacy in these patients and a personalized approach is therefore necessary. Importantly, given the enhanced infection risks associated with dialysis, current vaccines do not replace non-pharmacological measures to prevent infection.

PubMed Disclaimer

Conflict of interest statement

B.W. was funded by the Dr. Werner Jackstädt Foundation and received travel reimbursements and/or honoraria from Alexion, Chiesi, Hexal, Otsuka, TEVA, Sanofi and Wyeth. A.K. received travel reimbursements, honoria and/or grants from Ablynx, Advitos, Alexion, Amgen, Astellas, AstraZeneca, Baxter, Bayer Vital, Bristol Myers Squibb, B. Braun Avitum, Binding Site, Charité, Chiesi, Cyto Sorbents, Exthera Medical, GlaxoSmithKline, GE Healthcare, InflaRx, Jafron, Janssen-Cilag, Kyowa Kirin, Neovii Biotech, Novartis, Otsuka, Peripal, Pfizer, Reata Pharmaceuticals, Sanofi-Aventis, Shire-Takeda, Syneos Health and Vifor Fresenius. The other authors declare no competing interests.

References

    1. Goffin E, et al. COVID-19 related mortality in kidney transplant and hemodialysis patients: a comparative, prospective registry based study. Nephrol. Dial. Transplan. 2021 doi: 10.1093/ndt/gfab200. - DOI - PMC - PubMed
    1. Khoury DS, et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat. Med. 2021;27:1205–1211. doi: 10.1038/s41591-021-01377-8. - DOI - PubMed
    1. Chan L, Fuca N, Zeldis E, Campbell KN, Shaikh A. Antibody response to mRNA-1273 SARS-CoV-2 vaccine in hemodialysis patients with and without prior COVID-19. Clin. J. Am. Soc. Nephrol. 2021;16:1258–1260. doi: 10.2215/CJN.04080321. - DOI - PMC - PubMed
    1. Carr EJ, et al. Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients. Lancet. 2021;398:1038–1041. doi: 10.1016/S0140-6736(21)01854-7. - DOI - PMC - PubMed
    1. Pegu A, et al. Durability of mRNA-1273 vaccine-induced antibodies against SARS-CoV-2 variants. Science. 2021;373:1372–1377. doi: 10.1126/science.abj4176. - DOI - PMC - PubMed

Substances