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. 2021 Oct 11;31(19):R1115-R1117.
doi: 10.1016/j.cub.2021.08.064.

Gene regulation: Context is everything

Narendra P Singh  1
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Gene regulation: Context is everything

Narendra P Singh. Curr Biol. .
Free article

Abstract

How transcription factors regulate a distinct set of target genes in different cell types is a fundamental question. A new study demonstrates how Ultrabithorax, a Hox transcription factor, acts as both a repressor and an activator in a cell type-specific manner to alter chromatin accessibility and gene regulation.

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