Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2021 Nov;21(6):e604-e607.
doi: 10.7861/clinmed.2021-0308. Epub 2021 Oct 12.

Failing the frail: The need to broaden the COVID-19 case definition for geriatric patients

Affiliations
Observational Study

Failing the frail: The need to broaden the COVID-19 case definition for geriatric patients

Clare Hunt et al. Clin Med (Lond). 2021 Nov.

Abstract

The older population has a high mortality with COVID-19 and this cohort often presents atypically with infection. This study compares presenting complaints and observations of older patients with COVID-19 against the established case definition to determine whether the case definition should be broadened to better identify SARS-CoV-2 infection in this age group.This retrospective observational study analysed the presenting complaints and observations of people aged 70 years and over who were admitted to a district general hospital with confirmed SARS-CoV-2 infection from March to May 2020.Out of 225 patients, only 11.5% presented with the trio of cough, fever and breathlessness; 30.2% did not present with any of these symptoms (p<0.001). The most frequent atypical complaints were delirium (25%), general malaise (20%) and falls (19%). Only 32.4% recorded a temperature ≥37.6°C on admission while 20.4% were hypothermic with a temperature <36.4°C (p=0.0003).A significant proportion of older patients with COVID-19 presented with non-specific symptoms and observations. The high proportion of falls and delirium emphasises the need for early geriatrician input, awareness of COVID-19 as a differential for confusion in older patients and to include falls in the case definition for COVID-19 in the older population.

Keywords: COVID-19; delirium; falls; geriatric medicine; presenting complaints.

PubMed Disclaimer

Figures

Fig 1.
Fig 1.
Symptom categories and occurrence.

Similar articles

Cited by

References

    1. Docherty AB, Harrison EM, Green CA, et al. . Features of 20 133 UK patients in hospital with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ 2020;369:m1985. - PMC - PubMed
    1. Levin AT, Hanage WP, Owusu-Boaitey N, et al. . Assessing the age specificity of infection fatality rates for COVID-19: systematic review, meta-analysis, and public policy implications. Eur J Epidemiol 2020;35:1123–38. - PMC - PubMed
    1. Wester AL, Dunlop O, Melby KK, Dahle UR, Wyller TB. Age-related differences in symptoms, diagnosis and prognosis of bacteremia. BMC Infectious Diseases 2013;13:346. - PMC - PubMed
    1. Zheng Z, Peng F, Xu B, et al. . Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis. J Infect 2020;81:e16–25. - PMC - PubMed
    1. Poloni TE, Carlos AF, Cairati M, et al. . Prevalence and prognostic value of Delirium as the initial presentation of COVID-19 in the elderly with dementia: An Italian retrospective study. EClinicalMedicine 2020;26:100490. - PMC - PubMed

Publication types