Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021;10(4):232-242.
doi: 10.1007/s13671-021-00334-5. Epub 2021 Oct 6.

Management of Infectious Emergencies for the Inpatient Dermatologist

Affiliations
Review

Management of Infectious Emergencies for the Inpatient Dermatologist

Tulsi Patel et al. Curr Dermatol Rep. 2021.

Abstract

Purpose of review: There are various dermatologic emergencies stemming from bacterial, viral, and fungal etiologies that can present in the inpatient setting. This review summarizes the pathogenesis and diagnosis of infections with cutaneous involvement and highlights new therapies.

Recent findings: Clindamycin inhibits toxin formation and can be used as an adjunct therapy for the staphylococcal scalded syndrome. Isavuconazole therapy for mucormycosis infection is a less toxic alternative to amphotericin B.

Summary: Diagnosis of these infections is primarily guided by high clinical suspicion and early recognition can prevent dangerous sequelae. Treatment mainstays have been well-established, but there are adjunctive therapies that may potentially benefit the patient.

Keywords: Cutaneous manifestations of infection; Dermatologic emergencies; Dermatologic infection; Skin infection.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
The flaccid bullae with the following characteristics: wrinkly and scalded skin appearance, followed by re-epithelialization without scarring
Fig. 2
Fig. 2
The improvement of a case of mucormycosis over the period of 4 months
Fig. 3
Fig. 3
Disseminated cutaneous zoster, defined as over 20 lesions outside the primary and contiguous dermatomes

Similar articles

Cited by

References

    1. Schlievert PM, Shands KN, Dan BB, Schmid GP, Nishimura RD. Identification and characterization of an exotoxin from Staphylococcus aureus associated with toxic-shock syndrome. J Infect Dis. 1981;143(4):509–516. doi: 10.1093/infdis/143.4.509. - DOI - PubMed
    1. Seishima M, Kato G, Shibuya Y, Matsukawa S. Cytokine profile during the clinical course of toxic shock syndrome. Clin Exp Dermatol. 2009;34(8):e632–e635. doi: 10.1111/j.1365-2230.2009.03353.x. - DOI - PubMed
    1. McCormick JK, Yarwood JM, Schlievert PM. Toxic shock syndrome and bacterial superantigens: an update. Annu Rev Microbiol. 2001;55(1):77–104. doi: 10.1146/annurev.micro.55.1.77. - DOI - PubMed
    1. Reingold A, Hargrett N, Dan B, Shands K, Strickland B, Broome C. Nonmenstrual toxic shock syndrome: a review of 130 cases. Ann Intern Med. 1982;96(6_Part_2):871–874. doi: 10.7326/0003-4819-96-6-871. - DOI - PubMed
    1. Chesney PJ, Davis JP, Purdy WK, Wand PJ, Chesney RW. Clinical manifestations of toxic shock syndrome. Jama. 1981;246(7):741–748. doi: 10.1001/jama.1981.03320070025019. - DOI - PubMed

LinkOut - more resources