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Meta-Analysis
. 2022 Jan;32(1):170-185.
doi: 10.1007/s11695-021-05745-8. Epub 2021 Oct 12.

Roux-en-Y Gastric Bypass Vs Sleeve Gastrectomy in Super Obesity: a Systematic Review and Meta-Analysis

Sofia Raquel Gomes-Rocha  1 , André Manuel Costa-Pinho  2   3 , Carolina Coelho Pais-Neto  1 , André de Araújo Pereira  1   4 , Jorge Pedro Martins Nogueiro  1   4 , Silvestre Porfírio Ramos Carneiro  1   4 , Hugo Miguel Teixeira Ferraz Santos-Sousa  1   5 , Eduardo Jorge Lima-da-Costa  1   5 , Raquel Bouça-Machado  6 , John Rodrigues Preto  1   5 ; CRI-O Group
Affiliations
Meta-Analysis

Roux-en-Y Gastric Bypass Vs Sleeve Gastrectomy in Super Obesity: a Systematic Review and Meta-Analysis

Sofia Raquel Gomes-Rocha et al. Obes Surg. 2022 Jan.

Abstract

Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are safe procedures that may present sub-optimal results in superobesity (SO). A meta-analysis was performed aiming to summarize the available evidence on weight loss (primary outcome) and comorbidities resolution of LRYGB and LSG in patients with SO (BMI ≥ 50 kg/m2). From the 16 included studies, 7 integrated the meta-analysis. LRYGB showed a significantly higher weight loss at 6 to 12-months, but not after 24 months and a higher dyslipidemia resolution at 12 months. When compared with LSG, LRYGB achieved better weight loss after 6 and 12 months and higher dyslipidemia resolution after 1 year. There were no significant differences for resolution of the other co-morbidities studied.

Keywords: Bariatric surgery; Comorbidity resolution; LRYGB; LSG; Laparoscopic Roux-en-Y gastric bypass; Laparoscopic sleeve gastrectomy; Meta-analysis; Super obesity; Weight loss.

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