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Comment
. 2021 Oct 12;54(10):2185-2187.
doi: 10.1016/j.immuni.2021.09.007.

ILC1-like NK cells as matchmakers for DC-T cell interactions

Ana Stojanovic  1 , Adelheid Cerwenka  2
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ILC1-like NK cells as matchmakers for DC-T cell interactions

Ana Stojanovic et al. Immunity. .
Free article

Abstract

Both innate and adaptive immunity are orchestrated by multiple cell types, specialized cell lineages, and their spatiotemporal encounters. It is thought that adaptive-like NK cell responses to viral infection mainly involve circulating bona fide NK cells. In this issue of Immunity, Flommersfeld et al. (2021) identify a splenic-resident ILC1-like NK cell subset that facilitates CD8+ T cell-DC interactions during anti-viral defense.

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