Fat mesenchyme closes the neural-ILC2 circuit
- PMID: 34644555
- DOI: 10.1016/j.immuni.2021.09.012
Fat mesenchyme closes the neural-ILC2 circuit
Abstract
The immune milieu and neuronal activity each impact adipose metabolic health, yet their interplay remains largely undefined. In a recent issue of Nature, Cardoso et al. uncover a sympathetic neuro-mesenchymal-ILC2s circuit from brain-to-fat controlling obesity and glucose metabolism.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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Neuro-mesenchymal units control ILC2 and obesity via a brain-adipose circuit.Nature. 2021 Sep;597(7876):410-414. doi: 10.1038/s41586-021-03830-7. Epub 2021 Aug 18. Nature. 2021. PMID: 34408322 Free PMC article.
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