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Observational Study
. 2022 Jan;33(1):33-37.
doi: 10.1681/ASN.2021070936. Epub 2021 Oct 13.

COVID-19 Vaccine Type and Humoral Immune Response in Patients Receiving Dialysis

Pablo Garcia  1 , Shuchi Anand  1 , Jialin Han  1 , Maria E Montez-Rath  1 , Sumi Sun  2 , Tiffany Shang  2 , Julie Parsonnet  3   4 , Glenn M Chertow  1   4 , Brigitte Schiller  2 , Graham Abra  2
Affiliations
Observational Study

COVID-19 Vaccine Type and Humoral Immune Response in Patients Receiving Dialysis

Pablo Garcia et al. J Am Soc Nephrol. 2022 Jan.
No abstract available

Keywords: COVID-19; ESKD; SARS-CoV-2; dialysis; humoral; immunity; immunization; vaccine.

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Figures

Figure 1.
Figure 1.
RBD IgG responses before and after COVID-19 vaccination by vaccine type among patients receiving dialysis and a detectable total RBD Ig response. (A) The cohort with negative RBD Ig before vaccination, (B) the cohort with positive RBD Ig before vaccination. In these violin plot figures, each marker represents an individual semiquantitative RBD IgG index value by vaccine type in the time period related to vaccination. The index values are plotted on a log-scale, and the violin plot shows a mirrored representation of the distribution of the IgG index values on top of the individual index values. Green circles represent individuals vaccinated with mRNA1273, light blue with BNT162b2, and dark blue with Ad26.COV2.S. The IgG values range from 0.8 to 44, but index values <1 are considered nonreactive, and index values <10 (red dotted line in figures) are considered a “diminished” response. Patients without a detectable RBD IgG are placed in the <1 category (index value is set 0.8). The black boxes represent median values. The data plotted are among the patients with a total RBD Ig (i.e., seroconversion) after vaccination.
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Update of

References

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    1. Anand S, Montez-Rath ME, Han J, Garcia P, Cadden L, Hunsader P, et al. : Antibody response to COVID-19 vaccination in patients receiving dialysis. J Am Soc Nephrol 32: 2435–2438, 2021 - PMC - PubMed
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MeSH terms