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Review
. 2021 Aug 15;9(10):5869-5882.
doi: 10.1002/fsn3.2523. eCollection 2021 Oct.

Female infertility and herbal medicine: An overview of the new findings

Mohsen Akbaribazm  1 , Nader Goodarzi  2 , Mohsen Rahimi  3
Affiliations
Review

Female infertility and herbal medicine: An overview of the new findings

Mohsen Akbaribazm et al. Food Sci Nutr. .

Abstract

Infertility is defined as the failure to achieve a successful pregnancy after 12 months' sexual activity that affects 15%-17% of couples in the world and about 50% of them are related to female infertility factors. In this study, using the PRISMA checklist and MeSH keywords, 128 articles were extracted from various databases (PubMed, Cochrane library, WHO, Iranmedex, Science Direct, SID, and Google Scholar search engine) without language and time restrictions, and 128 articles were selected after eliminating duplicate studies. In this review, we present some solid evidence for role of herbal medicine in the treatment of female infertility. The results of this study showed that different parts of some plants are rich in polyphenolic compounds (isoflavones and flavonoids) and other compounds which are beneficial to in reproductive health in women. The compounds in these plants, along with regulating the female endocrine pathways, and improving symptoms of menopause, treat female reproductive disorders such as polycystic ovary syndrome (PCOS), premature ovarian failure (POF), endometriosis, hyperprolactinemia, and hypothalamic dysfunction; moreover, because of their anticancer, antioxidant, and antidepressant properties, they can be used in traditional medicine or in the pharmaceutical industry as safe compounds in women's health.

Keywords: endometriosis; female infertility; isoflavonoid; medicinal plants; menopause.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

FIGURE 1
FIGURE 1
PRISMA checklist. Flowchart of the entrance steps of the article information
FIGURE 2
FIGURE 2
Distribution of papers based on subject
FIGURE 3
FIGURE 3
Distribution of papers by publication year
See this image and copyright information in PMC

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