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Case Reports
. 2021 Oct 8:9:2050313X211050891.
doi: 10.1177/2050313X211050891. eCollection 2021.

Five days of fever and myocardial inflammation

Keli D Coleman  1 , Paul Benz  2 , Nirzar S Parikh  3 , Danny G Thomas  1 , David Segar  4 , Joseph Block  4 , Megan L Schultz  1
Affiliations
Case Reports

Five days of fever and myocardial inflammation

Keli D Coleman et al. SAGE Open Med Case Rep. .

Abstract

Multisystem inflammatory syndrome in children is an emerging pediatric illness associated with severe acute respiratory syndrome coronavirus 2 infection. The syndrome is rare, and evidence-based guidelines are lacking. This report reviews a patient who presented for medical care multiple times early in the course of his illness, thus offering near-daily documentation of symptoms and laboratory abnormalities. The patient did not have thrombocytopenia, anemia, or myocardial inflammation until the fifth day of fever. These laboratory abnormalities coincided with the onset of rash, conjunctival injection, vomiting, and diarrhea: clinical signs that could serve as indicators for when to obtain blood tests. The timing of this patient's onset of multisystem involvement suggests that testing for multisystem inflammatory syndrome in children after only 24 h of fever, as the Centers for Disease Control and Prevention recommends, may yield false-negative results. Testing for multisystem inflammatory syndrome in children after 4 days of fever may be more reliable.

Keywords: Infectious diseases; critical care/emergency medicine.

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Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Conjunctival injection.
Figure 2.
Figure 2.
The patient’s electrocardiogram showing sinus tachycardia and diffuse ST elevation.
See this image and copyright information in PMC

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