Workplace-related inhalation test - Specific inhalation challenge: S2k Guideline of the German Society for Occupational and Environmental Medicine e.V. (DGAUM), the German Society for Pneumology and Respiratory Medicine e.V. (DGP) and the German Society for Allergology and Clinical Immunology e.V. (DGAKI)

Abstract

Not available.

Keywords: allergic asthma; allergic sensitization; occupational asthma.

Figure 1.. Importance of SIC in the diagnosis of occupational allergic respiratory diseases. According to [41].

Figure 2a.. Protocol A – SIC Flowchart; simplified protocol. Indication: (1) Low spontaneous variability of lung function and (2) anamnestically or according to records justified assumption of an immediate reaction without delayed reaction to triggers at the workplace, but not to other non-specific irritant stimuli, see chapter 5.2.

Figure 2b.. Protocol B – Standard SIC procedure; simplified protocol with late measurement. Indication: (1) low spontaneous variability of pulmonary function and (2) history and record of an acute or delayed response to workplace triggers, but not to other nonspecific irritant stimuli. Determinations of FeNO and sputum cytology should be made at least on the 1^st and 3^rd days (before and 24 hours after exposure).

Figure 2c.. Protocol C – Flow chart of SIC in exceptional case; simplified protocol with control day. According to [41]. Indication: (1) high spontaneous variability of lung function and/or (2) anamnestically or according to records justified assumption of a non-specific reaction to irritative stimuli, without or with delayed reaction to triggers at the workplace, see Chapter 5.3. Determinations of FeNO and sputum cytology should be performed at least on the 1^st and 4^th day (before and 24 hours after exposure).