Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jan;32(1):57-66.
doi: 10.1007/s10895-021-02829-7. Epub 2021 Oct 14.

Effect of pH on Fluorescence Spectra of Coumarin Derivatives

Affiliations
Review

Effect of pH on Fluorescence Spectra of Coumarin Derivatives

Zain Ul Huda et al. J Fluoresc. 2022 Jan.

Abstract

Colourless crystalline solid coumarin with a bitter taste and sweet vanilla-like odor mostly acts as chemical protection against predators in plants. Anticoagulants (blood thinners), anti-fungicidal, anti-tumor and anti-inflammatory properties of coumarin are all used to treat skin diseases. Because of internal charge transfer (ICT), coumarin molecules displayed a solvatochromic effect in various solvents of varying polarity. The emission wavelength dependent fluorescence intensity was also affected by pH.

Keywords: Anticoagulants; Fluorescence; Internal charge transfer (ICT) and pH effect; Solvatochromic effect.

PubMed Disclaimer

References

    1. Tu Y et al (2021) Naturally occurring coumestans from plants, their biological activities and therapeutic effects on human diseases. Pharmacol Res 169:105615
    1. Yang Z et al (2009) Identification of coumarin-enriched Japanese green teas and their particular flavor using electronic nose. J Food Eng 92(3):312–316 - DOI
    1. Sahoo CR et al (2021) Coumarin derivatives as promising antibacterial agents. Arab J Chem 14(2):102922
    1. Conforti F, Marrelli M, Menichini F, Bonesi M, Statti G, Provenzano E, Menichini F (2009) Natural and synthetic furanocoumarins as treatment for vitiligo and psoriasis. Curr Drug Ther 4(1)
    1. Reddy DS, Kongot M, Kumar A (2021) Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity. Tuberculosis 127:102050

LinkOut - more resources