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. 2023 Jan;42(1):15-26.
doi: 10.1080/07315724.2021.1977735. Epub 2021 Oct 14.

Total Polyphenol Intake, Polyphenol Subtypes, and Prevalence of Hypertension in the CUME Cohort

Hillary Nascimento Coletro  1 , Josefina Bressan  2 , Amanda Popolino Diniz  1 , Helen Hermana Miranda Hermsdorff  2 , Adriano Marçal Pimenta  3 , Adriana Lúcia Meireles  4 , Raquel de Deus Mendonça  4 , Júlia Cristina Cardoso Carraro  4
Affiliations

Total Polyphenol Intake, Polyphenol Subtypes, and Prevalence of Hypertension in the CUME Cohort

Hillary Nascimento Coletro et al. J Am Nutr Assoc. 2023 Jan.

Abstract

Objective:Epidemiological studies have shown associations between polyphenol consumption and reduced risk of cardiovascular diseases. This study aimed to assess the association between polyphenol intake and the prevalence of hypertension.Methods:This cross-sectional study was performed on data from the Cohort of Universities of Minas Gerais (CUME) project. Participants completed an online food frequency questionnaire, and polyphenol intake was assessed using the Phenol-Explorer database and articles. Hypertension was determined by a medical diagnosis, having a blood pressure ≥ 130 mmHg/80 mmHg, or using antihypertensive drugs. Adjusted logistic regression models were used to estimate the odds ratios (ORs) and 95% confidence intervals (95% CIs) for the prevalence of hypertension.Results:The prevalence of hypertension was 39.57%, and the average intake of total polyphenols was 860.79 mg/day. The highest (5th quintile) intake of flavonoids (mean: 368.46mg/day; OR: 0.83; 95%CI 0.70; 0.97), hydroxybenzoic acids (mean: 379.38mg/day; OR: 0.77; 95%CI: 0.66;0.91), and flavonols (mean: 44.13mg/day; OR: 0.79; 95%CI: 0.67; 0.93) was inversely associated with hypertension prevalence, compared to the lowest intake (1st quintile).Conclusions:Our findings demonstrate that the intake of flavonoids, hydroxybenzoic acids, and flavonols is associated with a lower prevalence of hypertension.

Keywords: dietary polyphenols; flavonoids; flavonols; hydroxybenzoic acids; hypertension.

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